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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2021.12
- 수록면
- 323 - 328 (6page)
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초록· 키워드
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Naegleria fowleri is a free-living amoeba causing primary amoebic encephalitis. In this study, we analyzed how the N-aceytlglucosamine (GlcNAc) and D-galactose affected the interaction between Naegleria fowleri and methicillin-resistant Staphylococcus aureus (MRSA) or Escherichia coli O157:H7, and the interaction with bacteria when monosaccharides were treated with N. fowleri for a longer pre-incubation time. When GlcNAc was treated with N. fowleri for 1 hr, the E. coli association was almost the same as that of the control not treated with GlcNAc until the concentration of GlcNAc was 25 mM. However, the E. coli association was reduced by approximately 91% with 100 mM GlcNAc. E. coli invasion into N. fowleri showed statistical significance only in the group treated with 100 mM GlcNAc. The interaction when treated with galactose showed a very different pattern in the 50 mM galactose group than when treated with GlcNAc. In the MRSA interaction, a statistically significant decrease in association (76.3% by GlcNAc and 88.7% by galactose) and invasion (3.6% by GlcNAc and 9.3% by galactose) was shown by the concentration of two 100 mM monosaccharides. The group treated with monosaccharides at the same time showed almost no difference in all interactions from the group treated with monosaccharides at the same time. Taken together, it suggested that the effect of monosaccharides on the interaction of several Gram-negative or positive bacteria and the evidence that the interaction could be enhanced by longer pre-incubation time.
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참고문헌 (15)
참고문헌 신청
Alsam S / 2006 / Escherichia coli interactions with Acanthamoeba : a symbiosis with environmental and clinical implications / J Med Microbiol 55:689~694
Cervantes-Sandoval I / 2010 / Differences between Naegleria fowleri and Naegleria gruberi in expression of mannose and fucose glycoconjugates / Parasitol Res 106:695~701
Guzmán-Téllez P / 2020 / Naegleria fowleri and Naegleria gruberi 20S proteasome : identification and characterization / Eur J Cell Biol 99:151085
Huth S / 2017 / Adhesion forces and mechanics in mannose-mediated Acanthamoeba interactions / PLoS One 12:e0176207
Jahangeer M / 2020 / Naegleria fowleri : Sources of infection, pathophysiology, diagnosis, and management; a review / Clin Exp Pharmacol Physiol 47:199~212
Cervantes-Sandoval I / 2010 / Differences between Naegleria fowleri and Naegleria gruberi in expression of mannose and fucose glycoconjugates / Parasitol Res 106:695~701
Guzmán-Téllez P / 2020 / Naegleria fowleri and Naegleria gruberi 20S proteasome : identification and characterization / Eur J Cell Biol 99:151085
Huth S / 2017 / Adhesion forces and mechanics in mannose-mediated Acanthamoeba interactions / PLoS One 12:e0176207
Jahangeer M / 2020 / Naegleria fowleri : Sources of infection, pathophysiology, diagnosis, and management; a review / Clin Exp Pharmacol Physiol 47:199~212
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UCI(KEPA) : I410-ECN-0101-2022-510-000141849