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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 한국미생물생명공학회 Journal of Microbiology and Biotechnology Journal of Microbiology and Biotechnology 제30권 제5호
- 발행연도
- 2020.1
- 수록면
- 749 - 752 (4page)
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초록· 키워드
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In the search for novel, natural melanogenesis inhibitors, a new sesquiterpene, inularin, was isolated from the flowers of Inula britannica, and the structure was determined using spectroscopic and chemical methods. The antimelanogenic effects of inularin on B16F10 melanoma cells and zebrafish embryos were evaluated. Inularin dose-dependently reduced melanocyte-stimulating hormone-induced melanin production and L-DOPA oxidation in B16F10 cells. Zebrafish embryos were used to confirm the antimelanogenic activity. Inularin significantly decreased the pigmentation of embryos compared with untreated controls.
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참고문헌 (15)
참고문헌 신청
Bonaventure J / 2013 / Cellular and molecular mechanisms controlling the migration of melanocytes and melanoma cells / Pigment Cell Melanoma Res 26:316~325
Slominski A / 2004 / Melanin pigmentation in mammalian skin and its hormonal regulation / Physiol. Rev 84:1155~1228
Ebanks JP / 2009 / Mechanisms regulating skin pigmentation : the rise and fall of complexion coloration / Int. J. Mol. Sci 10:4066~4087
Nakagawa M / 1995 / Contact allergy to kojic acid in skin care products / Contact Dermatitis 32:9~13
Lee KT / 1997 / Biological screening of 100 plant extracts for cosmetic use(I) : inhibitory activities of tyrosinase and DOPA auto-oxidation / Int. J. Cosmet. Sci 19:291~298
Slominski A / 2004 / Melanin pigmentation in mammalian skin and its hormonal regulation / Physiol. Rev 84:1155~1228
Ebanks JP / 2009 / Mechanisms regulating skin pigmentation : the rise and fall of complexion coloration / Int. J. Mol. Sci 10:4066~4087
Nakagawa M / 1995 / Contact allergy to kojic acid in skin care products / Contact Dermatitis 32:9~13
Lee KT / 1997 / Biological screening of 100 plant extracts for cosmetic use(I) : inhibitory activities of tyrosinase and DOPA auto-oxidation / Int. J. Cosmet. Sci 19:291~298
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