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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2017.1
- 수록면
- 368 - 371 (4page)
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초록· 키워드
오류제보하기
Objective: It is unclear whether selective serotonin-reuptake inhibitors (SSRIs) can significantly increase the prolactin level. The purpose of this study was to identify the relationship between the prolactin level and the administration of SSRIs such as escitalopram and sertraline. An additional purpose was to determine whether the elevation of prolactin differs between escitalopram and sertraline treatment.
Methods: Serum prolactin levels were measured at baseline and after 3 months in 23 patients who received SSRI monotherapy with escitalopram (n=18) (ESC group) or sertraline (n=5) (SERT group) for 3 months.
Results: The prevalence of hyperprolactinemia at posttreatment was 34.8% (8/23). The overall pretreatment and posttreatment prolactin levels were 21.86±20.21 and 19.89±12.03 ng/mL (mean±SD), respectively, with ranges of 6.85−86.20 and 5.19−47.61 ng/mL. The pretreatment and posttreatment prolactin levels were 20.66±15.92 and 21.97±12.33 ng/mL, respectively, in the ESC group, and 26.18±33.75 and 12.43±7.76 ng/mL in the SERT group.
Conclusion: Clinicians should be aware that hyperprolactinemia can appear in patients receiving escitalopram or sertraline, even though they do not need routine monitoring for prolactin levels.
목차
등록된 정보가 없습니다.
참고문헌 (13)
참고문헌 신청
Coker F / 2010 / Antidepressant-induced hyperprolactinaemia: incidence, mechanisms and management / CNS Drugs 24 : 563 ~ 574
Emiliano AB / 2004 / From galactorrhea to osteopenia : rethinking serotonin-prolactin interactions / Neuropsychopharmacology 29 : 833 ~ 846
Gordon C / 1998 / Sertraline treatment does not increase plasma prolactin levels in healthy subjects / Psychopharmacology(Berl) 137 : 201 ~ 202
Hawken ER / 2006 / Effects of oral racemic citalopram on neuroendocrine responses / Prog Neuropsychopharmacol Biol Psychiatry 30 : 694 ~ 700
Kim S / 2013 / Serum prolactin and macroprolactin levels among outpatients with major depressive disorder following the administration of selective serotonin-reuptake inhibit
Emiliano AB / 2004 / From galactorrhea to osteopenia : rethinking serotonin-prolactin interactions / Neuropsychopharmacology 29 : 833 ~ 846
Gordon C / 1998 / Sertraline treatment does not increase plasma prolactin levels in healthy subjects / Psychopharmacology(Berl) 137 : 201 ~ 202
Hawken ER / 2006 / Effects of oral racemic citalopram on neuroendocrine responses / Prog Neuropsychopharmacol Biol Psychiatry 30 : 694 ~ 700
Kim S / 2013 / Serum prolactin and macroprolactin levels among outpatients with major depressive disorder following the administration of selective serotonin-reuptake inhibit
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