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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한정신약물학회 Clinical Psychopharmacology and Neuroscience Clinical Psychopharmacology and Neuroscience 제15권 제2호
- 발행연도
- 2017.1
- 수록면
- 126 - 131 (6page)
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초록· 키워드
오류제보하기
Objective: There are no evidence-based practices for treating anxiety in patients with acute coronary syndrome (ACS). Thus, we investigated the effects of escitalopram on anxiety in this population.
Methods: We enrolled 217 patients with ACS who met Diagnostic and Statistical Manual of Mental Disorders, 4th edition (DSM-IV) criteria for depressive disorders into a randomized double-blind placebo-controlled study. Patients received either escitalopram or placebo over a 24-week period. Anxiety symptoms were evaluated using the Hospital Anxiety and Depression Scale-anxiety subscale (HADS-A). A HADS-A score ＞7 was classified as an anxiety disorder. Baseline evaluations included sociodemographic and clinical characteristics, such as depressive symptoms, cardiovascular risk factors, and current cardiac status.
Results: Independent of improvements in depression and without any differences in safety profiles, escitalopram treatment was significantly more efficacious in treating and reducing anxiety than placebo over a 24-week period.
Conclusion: Escitalopram can be recommended as an effective and safe treatment option for anxiety in patients with ACS.
목차
등록된 정보가 없습니다.
참고문헌 (18)
참고문헌 신청
American Psychiatric Association / 1994 / Diagnostic and Statistical Manual of Mental Disorders, fourth edition (DSM-IV) / American Psychiatric Press Inc
Bjelland I / 2002 / The validity of the Hospital Anxiety and Depression Scale. An updated literature review / J Psychosom Res 52 : 69 ~ 77
Cepeda-Valery B / 2011 / Measuring health related quality of life in coronary heart disease : the importance of feeling well / Int J Cardiol 149 : 4 ~ 9
Fava M / 2008 / Difference in treatment outcome in outpatients with anxious versus nonanxious depression : a STAR*D report / Am J Psychiatry 165 : 342 ~ 351
Kessler RC / 2005 / Prevalence, severity, and comorbidity of 12-month DSM-IV disorders in the National Comorbidity Survey Replication / Arch Gen Psychiatry 62 : 617 ~ 627
Bjelland I / 2002 / The validity of the Hospital Anxiety and Depression Scale. An updated literature review / J Psychosom Res 52 : 69 ~ 77
Cepeda-Valery B / 2011 / Measuring health related quality of life in coronary heart disease : the importance of feeling well / Int J Cardiol 149 : 4 ~ 9
Fava M / 2008 / Difference in treatment outcome in outpatients with anxious versus nonanxious depression : a STAR*D report / Am J Psychiatry 165 : 342 ~ 351
Kessler RC / 2005 / Prevalence, severity, and comorbidity of 12-month DSM-IV disorders in the National Comorbidity Survey Replication / Arch Gen Psychiatry 62 : 617 ~ 627
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