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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2015.1
- 수록면
- 566 - 568 (3page)
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In our previous study, a prolactin elevation was more frequently in risperidone than in blonanserin; however, it was more often in blonanserin than in olanzapine. Therefore, while a rate of PRL rising is low to moderate, hyperprolactinemia is a considerable adverse effect in the blonanserin treatment. In this study, to examine detailed characteristics of hyperprolactinemia of blonanserin, we analyzed the prolactin data in six schizophrenic patients who were switched to blonanserin from other antipsychotics and followed for one year. As a result, blonanserin dose was clearly associated with serum prolactin level. The average prolactin level was almost normal when the mean blonanserin dosage was 8.0 mg/day. Regardless of the dose decrease of blonanserin, there were no remarkable changes in symptoms and social functions. Based on our findings, we conclude that low dose blonanserin medication may be useful for schizophrenia maintenance treatment without hyperprolactinemia and a high rate of relapse.
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등록된 정보가 없습니다.
참고문헌 (6)
참고문헌 신청
Deeks ED / 2010 / Blonanserin: a review of its use in the management of schizophrenia / CNS Drugs 24 : 65 ~ 84
Haddad PM / 2007 / Adverse effects of atypical antipsychotics: differential risk and clinical implications / CNS Drugs 21 : 911 ~ 936
Henderson DC / 2008 / Prolactin-related and metabolic adverse effects of atypical antipsychotic agents / J Clin Psychiatry 69 (Suppl 1) : 32 ~ 44
Takahashi S / 2013 / One-year follow-up study of psychotic patients treated with blonanserin: a case series / Asia Pac Psychiatry 5 : 164 ~ 167
Walters J / 2008 / Clinical questions and uncertainty--prolactin measurement in patients with schizophrenia and bipolar disorder / J Psychopharmacol 22 : 82 ~ 89
Haddad PM / 2007 / Adverse effects of atypical antipsychotics: differential risk and clinical implications / CNS Drugs 21 : 911 ~ 936
Henderson DC / 2008 / Prolactin-related and metabolic adverse effects of atypical antipsychotic agents / J Clin Psychiatry 69 (Suppl 1) : 32 ~ 44
Takahashi S / 2013 / One-year follow-up study of psychotic patients treated with blonanserin: a case series / Asia Pac Psychiatry 5 : 164 ~ 167
Walters J / 2008 / Clinical questions and uncertainty--prolactin measurement in patients with schizophrenia and bipolar disorder / J Psychopharmacol 22 : 82 ~ 89
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