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논문 기본 정보

자료유형
학술저널
저자정보
손창남 (계명대학교 의과대학 내과학교실)
저널정보
대한의사협회 대한의사협회지 대한의사협회지 제64권 제11호
발행연도
2021.11
수록면
772 - 777 (6page)
DOI
https://doi.org/10.5124/jkma.2021.64.11.772

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초록· 키워드

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Background: Gout is a common disease that is mainly caused by hyperuricemia. Although it is relatively easy to treat, adherence to drug treatment and the rate at which treatment targets are met is low. Current Concepts: For the treatment of acute gout attack, colchicine, nonsteroidal anti-inflammatory drugs, and glucocorticoids can be used alone or in combination depending on the severity of symptoms. To prevent gout attacks, patients are started on colchicine prior to or concurrent with treatment with uric acid?lowering drugs. The treatment is maintained until serum uric acid levels have returned to normal, and the patient has had no acute attacks for three to six months. Ultimately, the symptoms of gout are controlled in the long term by treating the patient’s hyperuricemia. For this purpose, allopurinol, febuxostat, and benzbromarone are used, and the side effects and contraindications for each drug should be checked. The goal for the treatment of chronic gout is to maintain a serum uric acid concentration below 6.0 mg/dL. Discussion and Conclusion: Patients visit the emergency departments of hospitals for sudden gout attacks. However, gout is a chronic disease that requires the lifelong use of uric acid?lowering agents. Therefore, it is necessary to educate patients on a serum urate-based treat-to-target approach.

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