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논문 기본 정보

자료유형
학술저널
저자정보
Cha Yonghan (Department of Orthopedic Surgery, Daejeon Eulji Medical Center, Eulji University School of Medicine, Daejeon, Korea) Lee Jongwon (Department of Orthopedic Surgery, Daejeon Eulji Medical Center, Eulji University School of Medicine, Daejeon, Korea) Choy Won-Sik (Department of Orthopedic Surgery, Daejeon Eulji Medical Center, Eulji University School of Medicine, Daejeon, Korea.) Lee Jae Sun (Advanced Therapy Center, Catholic Kwandong University International St. Mary’s Hospital, College of Medicine, Catholic Kwandong University) Lee Hyun Hee (Department of Orthopedic Surgery, Catholic Kwandong University International St. Mary’s Hospital, College of Medicine, Catholic Kwandong University, Incheon, Korea) Chae Dong-Sik (Department of Orthopedic Surgery, Catholic Kwandong University International St. Mary’s Hospital, College of Medicine, Catholic Kwandong University, Incheon, Korea)
저널정보
대한고관절학회 Hip and Pelvis Hip and Pelvis Vol.36 No.1
발행연도
2024.3
수록면
1 - 11 (11page)
DOI
10.5371/hp.2024.36.1.1

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초록· 키워드

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Gout is triggered by the accumulation of uric acid in the body, leading to hyperuricemia. Genetic, metabolic, and environ mental factors can influence this condition. Excessive uric acid buildup results in the formation of monosodium urate (MSU) crystals, which precipitate in specific areas of the body, including the joints, where they can cause symptoms of gout. While the acute and chronic symptoms of gout have been well-documented, diagnosis of gout affecting the hip joint poses signifi cant challenges. The global incidence of gout, the most prevalent form of inflammatory arthritis, is on the rise. Evaluation of the clinical signs, laboratory results, and imaging results is generally required for diagnosis of gout in cases where MSU crys tals have not been detected. Hyperuricemia is considered a primary cause of arthritis symptoms, and comprehensive guide lines for treatment are available. Therefore, the choice of medication is straightforward, and moderate effectiveness of treat ment has been demonstrated. Gout is a chronic disease, requiring lifelong uric acid-lowering medications, thus application of a treatment strategy based on the target blood uric acid concentration is necessary. Consequently, cases of gout will likely be observed more frequently by hip surgeons in clinical scenarios in the future. The objective of this review is to provide an over view of the pathophysiology of gout and subsequently examine recent advances in diagnostic methods and therapeutic agents based on an understanding of its underlying mechanisms. In addition, literature on gout-related issues affecting the hip joint, providing a useful reference for hip surgeons is examined.

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