지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2016.1
- 수록면
- 101 - 107 (7page)
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초록· 키워드
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Purpose: To evaluate the effect of platelet-rich plasma (PRP) eye drops in the treatment of recurrent cornealerosions (RCE).
Methods: A total of 47 eyes were included in this retrospective study. Clinical records of 20 consecutive patientswith RCE who had been treated with conventional lubricant eye drops (conventional treatment group) fromJune 2006 to December 2008 and 27 consecutive patients treated with autologous PRP eye drops in additionto lubricant eye drops (PRP eye drops treated group) from January 2009 to September 2014 were reviewed.
Major and minor recurrences were recorded and compared between two groups.
Results: This study included 31 men and 16 women. The mean age was 44.5 ± 14.5 years (range, 19 to 86years), and the mean follow-up duration was 14.9 ± 14.4 months (range, 6 to 64 months). Of the 27 casesin the PRP eye drops treated group, there were seven major recurrences in six eyes (22.2%) and ten minorrecurrences in seven eyes (25.9%). In contrast, 16 eyes (80.0%) from the 20 patients in the conventional lubricanteye drops treated group had major recurrences, and all patients in this group reported minor recurrences.
The mean frequency of recurrence was 0.06 ± 0.08 per month in the PRP eye drops treated group and 0.39 ±0.24 per month in the conventional treatment group (p = 0.003). No side effects were noted in any of the patientsover the follow-up period.
Conclusions: The use of PRP eye drops for the treatment of RCE was shown to be effective in reducing therecurrence rate without any significant complications.
목차
등록된 정보가 없습니다.
참고문헌 (34)
참고문헌 신청
Dursun D / 2001 / Treatment of recalcitrant recurrent corneal erosions with inhibitors of matrix metalloproteinase-9, doxycycline and corticosteroids / Am J Ophthalmol 132:8~13
Hope-Ross MW / 1994 / Oral tetracycline in the treatment of recurrent corneal erosions / Eye (Lond) 8(Pt 4):384~388
Buxton JN / 1983 / Superficial epithelial keratectomy in the treatment of epithelial basement membrane dystrophy:a preliminary report / Arch Ophthalmol 101:392~395
Soong HK / 2002 / Diamond burr superficial keratectomy for recurrent corneal erosions / Br J Ophthalmol 86:296~298
McLean EN / 1986 / Recurrent erosion:treatment by anterior stromal puncture / Ophthalmology 93:784~788
Hope-Ross MW / 1994 / Oral tetracycline in the treatment of recurrent corneal erosions / Eye (Lond) 8(Pt 4):384~388
Buxton JN / 1983 / Superficial epithelial keratectomy in the treatment of epithelial basement membrane dystrophy:a preliminary report / Arch Ophthalmol 101:392~395
Soong HK / 2002 / Diamond burr superficial keratectomy for recurrent corneal erosions / Br J Ophthalmol 86:296~298
McLean EN / 1986 / Recurrent erosion:treatment by anterior stromal puncture / Ophthalmology 93:784~788
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