지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한병리학회 Journal of Pathology and Translational Medicine Journal of Pathology and Translational Medicine 제43권 제4호
- 발행연도
- 2009.1
- 수록면
- 335 - 341 (7page)
이용수
초록· 키워드
오류제보하기
Background : C1q nephropathy (C1qN) is a controversial diagnostic entity defined by Jennette and Hipp in 1985. The prevalence is very low and a few large scale studies have been reported. Application of the criteria for clinical diagnostics of C1qN may cause confusion with other glomerulonephropathies, such as minimal change disease (MCD) or focal segmental
glomerulosclerosis (FSGS). In order to clarify the confusion with glomerulonephropathies, we did this study to identify the clinicopathological characteristics and the exact disease entity of C1qN. Methods : A total of 5,258 kidney biopsies at Kangnam St Mary’s Hospital were reviewed.
Twenty three cases (0.44%) met the criteria of C1qN. Twenty eight cases showing dominant C1q deposits without electron dense depostis (EDD) grouped as C1q+EDD-, and previously diagnosed typical cases of MCD and FSGS were selected for this study. Four groups were compared to each other with regard to the clinical and pathological aspects of the disease.
Results : C1qN patients had an average age of 30.4 years. Eighteen were males and 5 were females. Eighty seven percent had proteinuria and 18% had hematuria. By electron microscopy analysis, 100% had mesangial EDD and 47.8% showed foot process effacement. C1qN had some significant differences compared with C1q+EDD-, MCD and FSGS. Conclusions : C1qN
is clinically and morphologically different from MCD and FSGS. However, additional long term studies are needed to fully define C1qN from other glomerulonephritis with C1q deposits.
목차
등록된 정보가 없습니다.
참고문헌 (17)
참고문헌 신청
Fukuma Y / 2006 / Clinicopathologic correlation of C1q nephropathy in children / Am J Kidney Dis 47 : 412 ~ 418
Hisano S / 2008 / Clinicopathologic correlation and outcome of C1q nephropathy / Clin J Am Soc Nephrol 3 : 1637 ~ 1643
In Seok Lim / 2007 / Proteinuria in a Boy with Infectious Mononucleosis, C1q Nephropathy,and Dent’s Disease / Journal of Korean Medical Science 22 (5) : 928 ~ 931
Iskandar SS / 1991 / C1q nephropathy: a pediatric clinicopathologic s / Am J Kidney Dis 18 : 459 ~ 465
Jennette JC / 1985 / C1q nephropathy: a distinct pathologic entity usually causing nephrotic syndrome / Am J Clin Kidney Disease 6 : 103 ~ 110
Hisano S / 2008 / Clinicopathologic correlation and outcome of C1q nephropathy / Clin J Am Soc Nephrol 3 : 1637 ~ 1643
In Seok Lim / 2007 / Proteinuria in a Boy with Infectious Mononucleosis, C1q Nephropathy,and Dent’s Disease / Journal of Korean Medical Science 22 (5) : 928 ~ 931
Iskandar SS / 1991 / C1q nephropathy: a pediatric clinicopathologic s / Am J Kidney Dis 18 : 459 ~ 465
Jennette JC / 1985 / C1q nephropathy: a distinct pathologic entity usually causing nephrotic syndrome / Am J Clin Kidney Disease 6 : 103 ~ 110
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