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논문 기본 정보

자료유형
학술저널
저자정보
Mi Hye Park (Kyungpook National University) Meera Kim (Kyungpook National University)
저널정보
한국식품영양과학회 Preventive Nutrition and Food Science Preventive Nutrition and Food Science Vol.23 No.4
발행연도
2018.12
수록면
326 - 334 (9page)
DOI
10.3746/pnf.2018.23.4.326

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초록· 키워드

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In this study, in order to verify the use of mycelium as a new functional material, Rhynchosia nulubilis was cultivated with Ganoderma lucidum mycelium, and the biological activity of the culture extract was evaluated. Measurements of the 2,2-diphenyl-1-picrylhydrazyl radical scavenging activity and 2,2’-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) diammonium salt radical scavenging activity showed that the ethanol extract from Rhynchosia nulubilis cultivated with Ganoderma lucidum mycelium (RNGM) had significantly higher radical scavenging activity compared to the ethanol extract from Rhynchosia nulubilis (RN). The growth inhibition rate of RNGM against HeLa cells was 93.93% at 400μg/mL in the 3-(4,5-dimethylthiazol-2-yl)-2,5-dimethyl tetrazolium assay. RNGM effectively decreased nitric oxide production in lipopolysaccharide-treated RAW264.7 macrophage cells. The total polyphenol, total flavonoid, and the β-glucan contents of RNGM were higher than those of RN. These results demonstrated that increased total polyphenols, flavonoids, and β-glucan of Rhynchosia nulubilis during cultivation with the Ganoderma lucidum mycelium could increase the antioxidant and antiinflammatory activity and cytotoxicity of cancer cells.

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ABSTRACT
INTRODUCTION
MATERIALS AND METHODS
RESULTS AND DISCUSSION
REFERENCES

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