Identification and Genotypic Characterization of Potentially Pathogenic Acanthamoeba Isolated from Tap Water in Wuxi, China

Meixu Wang; Guangxu Sun; Yangkai Sun; Xiaomin You; Xiaoxue Li; Yang Cheng; Yinghua Xuan

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자료유형: 학술저널

저자정보: Meixu Wang (Jiangnan University) Guangxu Sun (Jiangnan University) Yangkai Sun (Jiangnan University) Xiaomin You (Jiangnan University) Xiaoxue Li (Jiangnan University) Yang Cheng (Jiangnan University) Yinghua Xuan (Jiangnan University)

저널정보: 대한기생충학열대의학회 Parasites, Hosts and Diseases The Korean Journal of Parasitology Vol.56 No.6

발행연도: 2018.12

수록면: 615 - 618 (4page)

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Members of genus Acanthamoeba are widely distributed in the environment. Some are pathogenic and cause keratitis and fatal granulomatous amoebic encephalitis. In this study, we isolated an Acanthamoeba CJW/W1 strain from tap water in Wuxi, Jiangsu Province, China. Its 18S rDNA was sequenced and a phylogenetic tree was constructed. The isolated cysts belonged to morphologic group II. Comparison of 18S rDNA sequences of CJW/W1 strain and other isolates showed high similarity (99.7%) to a clinical isolate Asp, KA/E28. A phylogeny analysis confirmed this isolate belonged to the pathogenic genotype T4, the most common strain associated with Acanthamoeba-related diseases. This is the first report of an Acanthamoeba strain isolated from tap water in Wuxi, China. Acanthamoeba could be a public health threat to the contact lens wearers and, therefore, its prevalence should be monitored.

#Acanthamoeba #tap water #Wuxi

참고문헌 (19)

참고문헌 신청

[학술지(정기간행물)] - Lass A / 2017 / Detection of Acanthamoeba spp. in water samples collected from natural water reservoirs, sewages, and pharmaceutical factory drains using LAMP and PCR in China / Sci Total Environ 584-585 : 489 ~ 494

[학술지(정기간행물)] - Corsaro D / 2017 / Update on Acanthamoeba jacobsi genotype T15, including full-length 18S rDNA molecular phylogeny / Parasitol Res 116 : 1273 ~ 1284

[학술지(정기간행물)] - Wang Y / 2014 / Current advances in diagnostic methods of Acanthamoeba keratitis / Chin Med J 127 : 3165 ~ 3170

[학술지(정기간행물)] - Risler A / 2013 / Genotyping and phylogenetic analysis of Acanthamoeba isolates associated with keratitis / Parasitol Res 112 : 3807 ~ 3816

[학술지(정기간행물)] - Gomes Tdos S / 2016 / Acanthamoeba spp. in Contact Lenses from Healthy Individuals from Madrid, Spain / PLoS One 11 : e0154246 ~

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