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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 한국식품영양과학회 Journal of Food Science and Nutrition Journal of Food Science and Nutrition Vol.4 No.1
- 발행연도
- 1999.3
- 수록면
- 52 - 56 (5page)
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초록· 키워드
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This study has examined the effects of Aralia elata Seemann ethanol extract on antioxidant enzyme systems in rats along with benzo(α)pyrene (B(α)P) administration. The ethanol extract of Aralia elata Seemann (50 ㎎/㎏ body wt.) was fed to rats for 4 weeks by stomach tubing. The extract administration increased antioxidant activities of glutathione sulfur transferase (GST) comparing to the control. Also total superoxide dismutase (SOD) and Cu, Zn-SOD activities were stimulated. Catalase activities were increased by 50% with the extract feeding compared to the control. Combined administration of B(α)P and the extract increased GST activity in B(α)P group. Although total SOD activity was decreased, Cu,Zn-SOD was greatly increased from 0.10 unit to 0.18 unit and catalase activity also was increased compared to the group of B(α)P. GST activity in CLE group was 1.32 unit, increased by 33% comparing to the group CL of 0.99 unit. Cu,Zn-SOD and catalase activities in the group fed high fat and ethanol extracts were increased by 25% and 39%, respectively comparing to the group of high fat. In addition, total SOD was decreased but, CU,Zn-SOD activity was increased from 0.09 unit to 0.18 unit. Catalase activity was 76.05 unit in the group of B(α)P and extract comparing to 65.26 units in B(α)P group. Serum α -tocopherol of rat was markedly increased by the extract. Administration of B(α)P reduced α -tocopherol levels in the serum, on the other hand, lard in the diet increased α -tocopherol levels in the serum. The above results indicate that Aralia bud exerts antioxidant functions in vivo against B(α)P. Further research may be necessary for the identification of the biologically active material.
목차
Abstract
INTRODUCTION
MATERIALS AND METHODS
RESULTS AND DISCUSSION
ACKNOWLEDGEMENTS
REFERENCES
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