지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2023.2
- 수록면
- 78 - 83 (6page)
이용수
초록· 키워드
오류제보하기
The use of an effective antimalarial drug is the cornerstone of malaria control. However, the development and spread of resistant Plasmodium falciparum strains have placed the global eradication of malaria in serious jeopardy. Molecular marker analysis constitutes the hallmark of the monitoring of Plasmodium drug-resistance. This study included 96 P. falciparum PCR-positive samples from southern Somalia. The P. falciparum chloroquine resistance transporter gene had high frequencies of K76T, A220S, Q271E, N326S, and R371I point mutations. The N86Y and Y184F mutant alleles of the P. falciparum multidrug resistance 1 gene were present in 84.7 and 62.4% of the isolates, respectively. No mutation was found in the P. falciparum Kelch-13 gene. This study revealed that chloroquine resistance markers are present at high frequencies, while the parasite remains sensitive to artemisinin (ART). The continuous monitoring of ART-resistant markers and in vitro susceptibility testing are strongly recommended to track resistant strains in real time.
목차
등록된 정보가 없습니다.
참고문헌 (0)
참고문헌 신청함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Sensitivity of Plasmodium falciparum to Antimalarial Drugs in Hainan Island, China
Parasites, Hosts and Diseases
2015 .02
-
Unraveling Haplotype Diversity of the Apical Membrane Antigen-1 Gene in Plasmodium falciparum Populations in Thailand
Parasites, Hosts and Diseases
2018 .04
-
Allelic Diversity and Geographical Distribution of the Gene Encoding Plasmodium falciparum Merozoite Surface Protein-3 in Thailand
Parasites, Hosts and Diseases
2015 .04
-
Blackwater Fever Followed by Severe Falciparum Malaria in a Child
Pediatric Infection and Vaccine
2017 .08
-
Genetic diversity of Plasmodium falciparum erythrocyte membrane protein 1 in field isolates: Correspondence
Parasites, Hosts and Diseases
2023 .08
-
Mixed Infection with Plasmodium falciparum and Plasmodium ovale in a Returned Traveller: the First Case in Korea
Journal of Korean Medical Science
2019 .01
-
An Alternative Method for Extracting Plasmodium DNA from EDTA Whole Blood for Malaria Diagnosis
Parasites, Hosts and Diseases
2018 .02
-
Late Parasitological Failure and Subsequent Isolated Gametocytemia of Uncomplicated Plasmodium falciparum Malaria in a Returned Traveler From Ghana, 2023
Journal of Korean Medical Science
2024 .06
-
Genetic diversity of Plasmodium falciparum erythrocyte membrane protein 1 in field isolates from central Myanmar
Parasites, Hosts and Diseases
2023 .02
-
Characteristics of Imported Malaria and Species of Plasmodium Involved in Shandong Province, China (2012-2014)
Parasites, Hosts and Diseases
2016 .08
-
Effect of Farnesyltransferase Inhibitor R115777 on Mitochondria of Plasmodium falciparum
Parasites, Hosts and Diseases
2015 .08
-
Intraleukocytic hemozoin pigments in complicated Plasmodium falciparum cerebral malaria
Blood Research
2015 .01
-
Molecular Markers for Sulfadoxine/Pyrimethamine and Chloroquine Resistance in Plasmodium falciparum in Thailand
Parasites, Hosts and Diseases
2022 .04
-
Allelic Diversity of MSP1 Gene in Plasmodium falciparum from Rural and Urban Areas of Gabon
Parasites, Hosts and Diseases
2015 .08
-
Anti-malarial effect of PJ extract by inhibiting platelet activation in rodent model
한국실험동물학회 학술발표대회 논문집
2022 .07
-
Antiplasmodial and Cytotoxic Activities of Toad Venoms from Southern Amazon, Brazil
Parasites, Hosts and Diseases
2016 .08
-
Plasmodium vivax Drug Resistance Genes; Pvmdr1 and Pvcrt-o Polymorphisms in Relation to Chloroquine Sensitivity from a Malaria Endemic Area of Thailand
Parasites, Hosts and Diseases
2015 .02
-
Diagnostic Performance of Three Rapid Diagnostic Test Kits for Malaria Parasite Plasmodium falciparum
Parasites, Hosts and Diseases
2020 .04
-
High Malaria Prevalence among Schoolchildren on Kome Island, Tanzania
Parasites, Hosts and Diseases
2015 .10
-
Performance Evaluation of Biozentech Malaria Scanner in Plasmodium knowlesi and P. falciparum as a New Diagnostic Tool
Parasites, Hosts and Diseases
2021 .04
이 논문의 저자 정보
최근 본 자료
댓글(0)
0
UCI(KEPA) : I410-ECN-0101-2023-513-000432039