지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2022.9
- 수록면
- 105 - 114 (10page)
- DOI
- 10.20307/nps.2022.28.3.105
이용수
초록· 키워드
오류제보하기
Tinospora crispa (L.) is a medicinal plant traditionally used to treat various ailments including diabetes. The stem has been widely studied for its antidiabetic properties, however the antidiabetic potential of its leaves has not been explored. This study investigates the antidiabetic properties of methanolic T. crispa stem and leaves extracts on alloxan-induced diabetic rats. The stems and leaves were extracted using Soxhlet extraction with methanol as solvent. Crude extracts were administered at 500 mg/kg body weight (BW) (high dose) and 250 mg/kg BW (low dose) via oral route to alloxan induced diabetic rats. T. crispa stem and leaves extracts was found to significantly reduce blood glucose following a twelve-week treatment period. The highest mean difference in blood glucose level was exhibited by animals in the high dose treated stem and low dose leaf extracts. Both extracts showed approximately 75% percentage recovery from hyperglycaemia. The highest regenerative capacity was observed in animals treated with the low dose leaf extract.
목차
Abstract
Introduction
Experimental
Result and Discussion
References
참고문헌 (22)
참고문헌 신청
Thomas, A.; Rajesh, E. K.; Kumar, D. S. Phytother. Res. 2016, 30, 357-366.
Zulkhairi Jr, A.; Abdah, M. A.; Kamal, N. H. M.; Nursakinah, I.; Moklas, M. A.; Hasnah, B.; Fazali, F.; Khairunnur, F. A.; Kamilah, K. A.; Zamree, M. S.; Shahidan, M. M. Malays. J. Nutr. 2008, 14, 173-187.
Noor, H.; Hammonds, P.; Sutton, R.; Ashcroft, S. J. Diabetologia 1989, 32, 354-359.
Ruan, C.; Lam, S.; Lee, S.; Su, M. Phytomedicine 2013, 20, 667-675.
Gao, Y.; Niu, Y.; Wang, F.; Hai, P.; Wang, F.; Fang, Y.; Xiong, W.; Liu, J. Nat. Prod. Bioprospec. 2016, 6, 247-255.
Zulkhairi Jr, A.; Abdah, M. A.; Kamal, N. H. M.; Nursakinah, I.; Moklas, M. A.; Hasnah, B.; Fazali, F.; Khairunnur, F. A.; Kamilah, K. A.; Zamree, M. S.; Shahidan, M. M. Malays. J. Nutr. 2008, 14, 173-187.
Noor, H.; Hammonds, P.; Sutton, R.; Ashcroft, S. J. Diabetologia 1989, 32, 354-359.
Ruan, C.; Lam, S.; Lee, S.; Su, M. Phytomedicine 2013, 20, 667-675.
Gao, Y.; Niu, Y.; Wang, F.; Hai, P.; Wang, F.; Fang, Y.; Xiong, W.; Liu, J. Nat. Prod. Bioprospec. 2016, 6, 247-255.
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
꽃송이버섯의 구성성분과 약리효과에 대한 리뷰
대한본초학회지(본초분과학회지)
2019 .01
-
Safety, Efficacy, and Physicochemical Characterization of Tinospora crispa Ointment : A Community-Based Formulation against Pediculus humanus capitis
Parasites, Hosts and Diseases
2017 .08
-
Synthesis of a New Zinc-Mixed Ligand Complex and Evaluation of Its Antidiabetic Properties in High Fat Diet: Low Dose Streptozotocin Induced Diabetic Rats
Diabetes and Metabolism Journal
2018 .01
-
Effect of Marsilea quadrifolia (L.) on carbohydrate metabolic enzymes in alloxan induced diabetic rats
Journal of Pharmaceutical Investigation
2018 .07
-
Assessment of In vitro Antioxidant, Antidiabetic and Cytotoxic Activities of Sphaeranthus africanus Extracts
Natural Product Sciences
2023 .06
-
Anti-Diabetic Effects of an Ethanol Extract of Cassia Abbreviata Stem Bark on Diabetic Rats and Possible Mechanism of Its Action - Anti-diabetic Properties of Cassia abbreviata -
Journal of Pharmacopuncture
2017 .01
-
꽃송이버섯 추출물의 Monosodium Iodoacetate로 유도된 골관절염 억제 효과
생약학회지(Korean Journal of Pharmacognosy)
2018 .09
-
Modulation of Inflammatory Cytokines and Islet Morphology as Therapeutic Mechanisms of Basella alba in Streptozotocin-Induced Diabetic Rats
Toxicological Research
2018 .10
-
오가나무 잎, 줄기의 항산화 및 항당뇨 효능 분석
생약학회지(Korean Journal of Pharmacognosy)
2019 .06
-
Urtica Dioica and Lamium Album Decrease Glycogen Synthase Kinase-3 beta and Increase K-Ras in Diabetic Rats
Journal of Pharmacopuncture
2019 .01
-
경옥고의 원방과 가미방 익수영진고가(加)꽃송이버섯이 항산화, 면역력 활성 및 기호도에 미치는 영향
대한본초학회지(본초분과학회지)
2016 .01
-
마치현 부위별 에탄올 추출물의 항산화 활성
대한본초학회지(본초분과학회지)
2019 .01
-
Antidiabetic effect of Luffa cylindrical extract against the streptozotocin induced diabetes via alteration of glucose transporter 2 and sodium-glucose cotransporter 1
Annals of Hepato-Biliary-Pancreatic Surgery
2021 .12
-
Subacute oral toxicity of Dendropanax morbiferus H.Lév leaf extracts in Sprague-Dawley rats
예방수의학회지
2023 .03
-
Reversal of Hypoglycemia Unawareness with a Single-donor, Marginal Dose Allogeneic Islet Transplantation in Korea: A Case Report
Journal of Korean Medical Science
2015 .01
-
Toxicological assessment of Bromochlorophene: single and repeated-dose 28-day oral toxicity study in Sprague–Dawley rats
한국실험동물학회 학술발표대회 논문집
2021 .01
-
Mulberry leaf extract displays antidiabetic activity in db/db mice via Akt and AMP-activated protein kinase phosphorylation
한국실험동물학회 학술발표대회 논문집
2018 .07
-
Aristolochia ringens extract ameliorates oxidative stress and dyslipidaemia associated with streptozotocin-induced hyperglycaemia in rats
셀메드
2018 .08
-
Professional Continuous Glucose Monitoring Reveals Nocturnal Hypoglycemia in Patients with Type 2 Diabetes Mellitus and Cardiovascular Disease Treated with Oral Antidiabetics
Korean Journal of Family Medicine
2021 .01
-
Therapeutic mechanisms and beneficial effects of non-antidiabetic drugs in chronic liver diseases
Clinical and Molecular Hepatology
2022 .07
이 논문의 저자 정보
이 논문과 함께 이용한 논문
Inhibition of α-Glucosidase by Abietane-Type Diterpenoids Isolated from Roots of Salvia miltiorrhiza
Nguyen Viet Phong
,
Le Thi Thanh
,
Mi Jeong Kwon
외 3명
Natural Product Sciences
2023
.12
Isolation and Activity Evaluation of Peptides with Anti-hypertensive Activity from Commercial Enzymatic Flounder Fish Hydrolysate
Ju-Young Ko
,
Ji-Hyeok Lee
,
Hwan-Hee Sim
외 2명
Natural Product Sciences
2023
.12
Antioxidant and Anti-inflammatory Activities of Rumex acetosa
Dong-Min Kang
,
Hye-Jin Kim
,
Woo Sung Pa
외 7명
Natural Product Sciences
2023
.12
Limonium tetragonum Reduces Osteoclast Formation and Resorption through Mitogen-activated Protein Kinase-c-Fos-NFATc1 Signaling Pathways
Sa
,
oj Kuma
,
Sh
외 5명
Natural Product Sciences
2023
.12
NO Production Inhibition of Lignans from Vietnamese Schisandra sphenanthera Rehd. et Wils. Fruits
Hong Khuyen Thi Pham
,
Phu Chi Hieu T
,
uong
외 5명
Natural Product Sciences
2023
.12
최근 본 자료
댓글(0)
0