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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한마취통증의학회(구 대한마취과학회) Korean Journal of Anesthesiology Korean Journal of Anesthesiology Vol.68 No.2
- 발행연도
- 2015.1
- 수록면
- 136 - 140 (5page)
이용수
초록· 키워드
오류제보하기
Background: This study compared intubating conditions and the onset time associated with administration of cisatracurium,a nondepolarizing neuromuscular blocker with a relatively slow onset, according to prior injection of one of twointravenous anesthetic agents: propofol or etomidate.
Methods: Forty-six female patients, undergoing general anesthesia and endotracheal intubation for elective surgery, wererandomized to two groups; group P were administered propofol (2 mg/kg) prior to cisatracurium (0.2 mg/kg); group Ewere administered etomidate (0.3 mg/kg) prior to cisatracurium (0.2 mg/kg). We measured intubating conditions andthe onset time according to the types of intravenous anesthetic administered. Measurements of heart rate (HR), systolicblood pressure (SBP) and diastolic blood pressure (DBP) were taken immediately prior to induction; immediately and 1min after IV anesthetic administration; and immediately and 1, 2, 3, 4, 5, 7, and 15 min after endotracheal intubation.
Results: Intubating conditions were superior in group E compared with group P (P = 0.009). The average onset time ofcisatracurium was more rapid in group E (155.74 ± 32.92 s vs. 185.26 ± 38.57 s in group P; P = 0.008). There were nogroup differences in SBP, DBP, and HR following intravenous anesthetic drug injection and endotracheal intubation.
However, SBP and DBP were substantially higher in group E after endotracheal intubation.
Conclusions: Etomidate improves intubating conditions and provide a more rapid onset time of cisatracurium duringanesthetic induction compared to propofol.
목차
등록된 정보가 없습니다.
참고문헌 (16)
참고문헌 신청
Welch RM / 1995 / The in vitro degradation of cisatracurium, the R, cis-R’-isomer of atracurium, in human and rat plasma / Clin Pharmacol Ther 58:132~142
Doenicke A / 1997 / The lack of histamine release with cisatracurium : a double-blind comparison with vecuronium / Anesth Analg 84:623~628
Kirov K / 2004 / Comparison of the neuromuscular blocking effect of cisatracurium and atracurium on the larynx and the adductor pollicis / Acta Anaesthesiol Scand 48:577~581
Hyunjung Lee / 2013 / Anesthesiologist’s satisfaction using between cisatracurium and rocuronium for the intubation in the anesthesia induced by remifentanil and propofol / Korean Journal of Anesthesiology 64(1):34~39
Fuchs-Buder T / 1998 / Thiopental or etomidate for rapid sequence induction with rocuronium / Br J Anaesth 80:504~506
Doenicke A / 1997 / The lack of histamine release with cisatracurium : a double-blind comparison with vecuronium / Anesth Analg 84:623~628
Kirov K / 2004 / Comparison of the neuromuscular blocking effect of cisatracurium and atracurium on the larynx and the adductor pollicis / Acta Anaesthesiol Scand 48:577~581
Hyunjung Lee / 2013 / Anesthesiologist’s satisfaction using between cisatracurium and rocuronium for the intubation in the anesthesia induced by remifentanil and propofol / Korean Journal of Anesthesiology 64(1):34~39
Fuchs-Buder T / 1998 / Thiopental or etomidate for rapid sequence induction with rocuronium / Br J Anaesth 80:504~506
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