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논문 기본 정보

자료유형
학술저널
저자정보
Jae Hyun Kim (Kosin University College of Medicine) 변상환 (고신대학교 의과대학 내과학교실) Youn Jung Choi (Kosin University College of Medicine) Hye Jung Kwon (Kosin University College of Medicine) Kyoungwon Jung (Kosin University College of Medicine) Sung Eun Kim (Kosin University College of Medicine) Moo In Park (Kosin University College of Medicine) 문원 (고신대학교) Seun Ja Park (Kosin University College of Medicine)
저널정보
대한소화기내시경학회 Clinical Endoscopy Clinical Endoscopy 제53권 제5호
발행연도
2020.1
수록면
555 - 561 (7page)

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Background/Aims: In this study, we compared the efficacy and safety of etomidate with those of propofol or midazolam for themaintenance of sedation during endoscopy. Methods: The study enrolled patients who underwent sedative endoscopy in our hospital and divided them into three groups. Patients in each group were administered midazolam as induction therapy and were subsequently administered either midazolam(M + M group), propofol (M + P group), or etomidate (M + E group) as maintenance medication. The primary outcome was overallcardiovascular and respiratory adverse events. Results: In total, 105 patients who underwent sedative endoscopic examination were enrolled. The outcomes related to the procedureand sedation were not significantly different among the groups. Overall cardiovascular and respiratory adverse events were observedin 9 patients (25.7%) in the M + M group, 8 patients (23.5%) in the M + P group, and 10 patients (27.8%) in the M + E group. Thelogistic regression analysis revealed that etomidate use was not an independent risk factor for overall cardiovascular and respiratoryadverse events. Conclusions: The outcomes following the use of etomidate for maintenance after induction with midazolam for sedation in uppergastrointestinal endoscopy were not inferior to those following midazolam or propofol use from the perspectives of safety andefficacy.

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