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- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2020.1
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This study compared the anthelminthic effects of three different brands of praziquantel being used in Sudan against Schistosoma haematobium (S. haematobium) infection. We enrolled 1,286 schoolchildren from six primary schools and examined their urine samples for eggs of S. haematobium at the baseline survey and follow-up two weeks after administering the medication. The schoolchildren were divided into three groups based on the three brands of praziquantel (different material production), with two school children for one brand. The overall baseline prevalence of S. haematobium infection was 15.5%. Two weeks after treatment with brands A, B, and C of praziquantel, cure rates were 87.1%, 82.4% and 83.8% respectively, and the egg-reduction rates were 69.0%, 81.0% and 70.6% respectively. There was no statistically significant difference in cure rates and egg-reduction rates between the three brands. We conclude that the three different commercial brands of praziquantel used in Sudan have similar anthelminthic effects on S. haematobium.
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참고문헌 (15)
참고문헌 신청
채종일 / 2013 / Praziquantel Treatment in Trematode and Cestode Infections: An Update / Infection and Chemotherapy 45(1):32~43
Gryseels B / 2012 / Schistosomiasis / Infect Dis Clin North Am 26(2):383~397
이양규 / 2020 / Case Report of Urinary Schistosomiasis in a Returned Traveler in Korea / The Korean Journal of Parasitology 58(1):51~55
Kabuyaya M / 2018 / Efficacy of praziquantel treatment regimens in pre-school and school aged children infected with schistosomiasis in sub-Saharan Africa : a systematic review / Infect Dis Poverty 7(1):73
Zwang J / 2017 / Efficacy and safety of praziquantel 40 mg/kg in preschool-aged and school-aged children : a meta-analysis / Parasit Vectors 10(1):47
Gryseels B / 2012 / Schistosomiasis / Infect Dis Clin North Am 26(2):383~397
이양규 / 2020 / Case Report of Urinary Schistosomiasis in a Returned Traveler in Korea / The Korean Journal of Parasitology 58(1):51~55
Kabuyaya M / 2018 / Efficacy of praziquantel treatment regimens in pre-school and school aged children infected with schistosomiasis in sub-Saharan Africa : a systematic review / Infect Dis Poverty 7(1):73
Zwang J / 2017 / Efficacy and safety of praziquantel 40 mg/kg in preschool-aged and school-aged children : a meta-analysis / Parasit Vectors 10(1):47
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