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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2015.6
- 수록면
- 271 - 277 (7page)
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초록· 키워드
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The genetic diversity of Schistosoma haematobium remains largely unstudied in comparison to that of Schistosoma mansoni. To characterize the extent of genetic diversity in S. haematobium among its definitive host (humans), we collected S. haematobium eggs from the urine of 73 infected schoolchildren at 5 primary schools in White Nile State, Sudan, and then performed a randomly amplified polymorphic DNA marker ITS2 by PCR-RFLP analysis. Among 73 S. haematobium egg-positive cases, 13 were selected based on the presence of the S. haematobium satellite markers A4 and B2 in their genomic DNA, and used for RFLP analysis. The 13 samples were subjected to an RFLP analysis of the S. haematobium ITS2 region; however, there was no variation in size among the fragments. Compared to the ITS2 sequences obtained for S. haematobium from Kenya, the nucleotide sequences of the ITS2 regions of S. haematobium from 4 areas in Sudan were consistent with those from Kenya (> 99%). In this study, we demonstrate for the first time that most of the S. haematobium population in Sudan consists of a pan-African S. haematobium genotype; however, we also report the discovery of Kenyan strain inflow into White Nile, Sudan.
목차
Abstract
INTRODUCTION
MATERIALS AND METHODS
RESULTS
DISCUSSION
REFERENCES
참고문헌 (14)
참고문헌 신청
[학술지(정기간행물)] - Van der Werf MJ / 2003 / Quantification of clinical morbidity associated with schistosome infection in sub-Saharan Africa / Acta Trop 86 : 125 ~ 139
[학술지(정기간행물)] - Lee YH / 2015 / Reduction of urogenital schistosomiasis with an integrated control project in Sudan / PLoS Negl Trop Dis 9 : e3423 ~
[학술지(정기간행물)] - Ismail H / 2014 / Prevalence, risk factors, and clinical manifestations of schistosomiasis among school children in the White Nile River basin, Sudan / Parasit Vectors 7 : 478 ~
[학술지(정기간행물)] - Norton AJ / 2010 / Genetic consequences of mass human chemotherapy for Schistosoma mansoni: population structure pre- and post-praziquantel treatment in Tanzania / Am J Trop Med Hyg 83 : 951 ~ 957
[학술지(정기간행물)] - Gower CM / 2011 / Population genetics of Schistosoma haematobium: development of novel microsatellite markers and their application to schistosomiasis control in Mali / Parasitology 138 : 978 ~ 994
[학술지(정기간행물)] - Lee YH / 2015 / Reduction of urogenital schistosomiasis with an integrated control project in Sudan / PLoS Negl Trop Dis 9 : e3423 ~
[학술지(정기간행물)] - Ismail H / 2014 / Prevalence, risk factors, and clinical manifestations of schistosomiasis among school children in the White Nile River basin, Sudan / Parasit Vectors 7 : 478 ~
[학술지(정기간행물)] - Norton AJ / 2010 / Genetic consequences of mass human chemotherapy for Schistosoma mansoni: population structure pre- and post-praziquantel treatment in Tanzania / Am J Trop Med Hyg 83 : 951 ~ 957
[학술지(정기간행물)] - Gower CM / 2011 / Population genetics of Schistosoma haematobium: development of novel microsatellite markers and their application to schistosomiasis control in Mali / Parasitology 138 : 978 ~ 994
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UCI(KEPA) : I410-ECN-0101-2016-513-001617800