메뉴 건너뛰기
.. 내서재 .. 알림
소속 기관/학교 인증
인증하면 논문, 학술자료 등을  무료로 열람할 수 있어요.
한국대학교, 누리자동차, 시립도서관 등 나의 기관을 확인해보세요
(국내 대학 90% 이상 구독 중)
로그인 회원가입 고객센터 ENG
주제분류

추천
검색
질문

논문 기본 정보

자료유형
학술저널
저자정보
Sung-Kuk Kim (Rural Development Administration) Sang Mi Han (Rural Development Administration) Se Gun Kim (Rural Development Administration) Hyo Young Kim (Rural Development Administration) Sik Ryu (Rural Development Administration) Soon Ok Woo (Rural Development Administration)
저널정보
한국양봉학회 Journal of Apiculture Journal of Apiculture Vol.36 No.4
발행연도
2021.11
수록면
243 - 250 (8page)
DOI
10.17519/apiculture.2021.11.36.4.243

이용수

표지
📌
연구주제
📖
연구배경
🔬
연구방법
🏆
연구결과
AI에게 요청하기
추천
검색
질문

이 논문의 연구 히스토리 (2)

초록· 키워드

오류제보하기
The study investigated the anti-inflammatory effects of propolis components on Raw264.7 macrophage cells. There were nine representative propolis components selected such as pinocembrin, quercetin, chrysin, naringin, gallic acid, p-coumaric acid, cinnamic acid, caffeic acid and CAPE. The cell cytotoxicity evaluation of diluted propolis components was determined by EZ-cytox cell viability assay. The anti-inflammation factors of propolis components were determined by confirming NO levels. All propolis components were able to decrease the generation of NO by LPS stimulation as inflammation inducer. However, quercetin, chrysin and CAPE components were significantly decreased the generation of NO and have synergistic effects for inflammation response. The expression of iNOS as inflammatory protein, IL-1β as representative cytokine and NF-κB as immune signaling molecule was evaluated using Western blotting. Quercetin, chrysin and CAPE involving inflammation response reduction play different role protein in expression in the cells. The results showed that propolis components have anti-inflammatory effects on Raw264.7 and each component may be related to immune-regulation. Thus, each propolis component may be used as a source of health-functional food materials for anti-inflammation response.

목차

Abstract
INTRODUCTION
MATERIALS AND METHODS
RESULTS AND DISCUSSION
CONCLUSION
LITERATURE CITED

참고문헌 (26)

참고문헌 신청

함께 읽어보면 좋을 논문

논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!

이 논문의 저자 정보

이 논문과 함께 이용한 논문

최근 본 자료

전체보기

댓글(0)

0

UCI(KEPA) : I410-ECN-0101-2022-527-000067761