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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2021.1
- 수록면
- 603 - 613 (11page)
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This research improved the growth potential of Bifidobacterium animalis subsp lactis strain JNU306, a commercial medium that is appropriate for large-scale production, in yeast extract, soy peptone, glucose, L-cysteine, and ferrous sulfate. Response surface methodology (RSM) was used to optimize the components of this medium, using a central composite design and subsequent analyses. A second-order polynomial regression model, which was fitted to the data at first, significantly lacked fitness. Thus, through further analyses, the model with linear and quadratic terms plus two-way, three-way, and four-way interactions was selected as the final model. Through this model, the optimized medium composition was found as 2.8791% yeast extract, 2.8030% peptone soy, 0.6196% glucose, 0.2823% L-cysteine, and 0.0055% ferrous sulfate, w/v. This optimized medium ensured that the maximum biomass was no lower than the biomass from the commonly used blood-liver (BL) medium. The application of RSM improved the biomass production of this strain in a more cost-effective way by creating an optimum medium. This result shows that B. animalis subsp lactis JNU306 may be used as a commercial starter culture in manufacturing probiotics, including dairy products.
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참고문헌 (21)
참고문헌 신청
Kantha D. Arunachalam / 1999 / Role of Bifidobacteria in nutrition, medicine and technology / Nutrition Research 19(10):1559~1597
R.I. Dave / 1996 / Evaluation of Media for Selective Enumeration of Streptococcus thermophilus, Lactobacillus delbrueckii ssp. bulgaricus, Lactobacillus acidophilus, and Bifidobacteria / Journal of Dairy Science 79(9):1529~1536
L. Masco / 2005 / Culture-dependent and culture-independent qualitative analysis of probiotic products claimed to contain bifidobacteria / International Journal of Food Microbiology 102(2):221~230
Marco Ventura / 2004 / Bifidobacterium lactis DSM 10140: identification of the atp (atpBEFHAGDC) operon and analysis of its genetic structure, characteristics, and phylogeny / Applied and Environmental Microbiology 70(5):3110~3121
Borja Sánchez / 2007 / Adaptation and response of Bifidobacterium animalis subsp. lactis to bile: a proteomic and physiological approach / Applied and Environmental Microbiology 73(21):6757~6767
R.I. Dave / 1996 / Evaluation of Media for Selective Enumeration of Streptococcus thermophilus, Lactobacillus delbrueckii ssp. bulgaricus, Lactobacillus acidophilus, and Bifidobacteria / Journal of Dairy Science 79(9):1529~1536
L. Masco / 2005 / Culture-dependent and culture-independent qualitative analysis of probiotic products claimed to contain bifidobacteria / International Journal of Food Microbiology 102(2):221~230
Marco Ventura / 2004 / Bifidobacterium lactis DSM 10140: identification of the atp (atpBEFHAGDC) operon and analysis of its genetic structure, characteristics, and phylogeny / Applied and Environmental Microbiology 70(5):3110~3121
Borja Sánchez / 2007 / Adaptation and response of Bifidobacterium animalis subsp. lactis to bile: a proteomic and physiological approach / Applied and Environmental Microbiology 73(21):6757~6767
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