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논문 기본 정보

자료유형
학술저널
저자정보
Kim Seungho (Department of Medical & Biological Engineering Kyungpook National University) Lee Sang Won (Department of Psychiatry Kyungpook National University Chilgok Hospital) Cha Hyunsil (Department of Medical & Biological Engineering Kyungpook National University) Kim Eunji (Department of Medical & Biological Engineering Kyungpook National University) Chang Yongmin (Department of Medical & Biological Engineering Kyungpook National University) Lee Seung Jae (Department of Psychiatry School of Medicine Kyungpook National University)
저널정보
대한신경정신의학회 PSYCHIATRY INVESTIGATION PSYCHIATRY INVESTIGATION 제18권 제6호
발행연도
2021.1
수록면
545 - 552 (8page)

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Objective Although cognitive models of obsessive-compulsive disorder (OCD) fall into two categories: cognitive deficit models and dysfunctional belief models, these approaches have their own ways and have hardly been reconciled. Therefore, this study aimed to investigate the potential relationships between cognitive deficit (using the Wisconsin Card Sorting Task, WCST) and dysfunctional belief (measured by scales of dysfunctional beliefs) mediated by neural activity in OCD patients. Methods Thirty OCD patients and 30 healthy participants performed the WCST condition and a baseline MATCH condition during the 3T-functional magnetic resonance imaging (fMRI) acquisition. Results Engagement of additional frontoparietal networks with poorer performance of WCST was found during the fMRI scan in OCD patients. Selected regions of interest from activated regions have positive relationships with dysfunctional beliefs and with the unacceptable thoughts symptom dimension in the OCD group. Conclusion Findings suggest that alteration in frontoparietal networks related to cognitive deficits can be associated with dysfunctional beliefs while performing conventional neurocognitive tasks and this association with dysfunctional beliefs may be pronounced in the unacceptable thoughts domain-dominant OCD patients.

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