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- 자료유형
- 학술대회자료
- 저자정보
- 발행연도
- 2021.7
- 수록면
- 205 - 205 (1page)
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Alzheimer"s disease (AD) is one of the most neurodegenerative disorders with severe cognitive impairments such as memory loss. In the region of cortex and hippocampus of AD patients, aggregation of misfolded amyloid-beta (Aβ) and hyperphosphorylated tau proteins are frequently observed. These abnormalities are well known as classical hallmarks of AD and are considered as main targets for AD treatments. In this study, we report that the fucoxanthin extracted microalgae Phaeodactylum tricornutum have potential effects for AD treatments. Fucoxanthin prevented the aggregation of both A β and hyperphosphorylated tau, specifically decreasing the levels of oligomeric forms of them. It is also showed that pre-aggregated Aβ and tau ... 전체 초록 보기
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