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논문 기본 정보
- 자료유형
- 학술대회자료
- 저자정보
- 발행연도
- 2021.7
- 수록면
- 188 - 188 (1page)
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Decamethylcyclopentasiloxane(D5) is one of the most common chemical ingredients for cosmetic products, cleansing agents, hairdye, dry cleaning solvent and personal hygiene supplies. D5 is also known as estrogenic chemical. It can be absorbed through skin, airosol, and even oraly. People are exposed to D5 in daily environment. However, the risk of prenatal exposure to D5 has not yet been fully understood. Recent research shows that imbalance of dam’s estrogen induces brain development disorder, in this study the effect of prenatal exposure of D5 on brain development were assessed by behavioral test of their pup. According to previous study, the estimated amount of daily exposure of D5 to human is around 0.6mg/kg. Also, the systematical absorption ratio of D5 by oral is 10% in mice. Thus, we treated 3, 6, 12 mg/kg of D5 with corn oil per a day to pregnant female mice from E10 through E19. A ... 전체 초록 보기
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