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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 한국식품영양과학회 Preventive Nutrition and Food Science Preventive Nutrition and Food Science Vol.25 No.4
- 발행연도
- 2020.12
- 수록면
- 375 - 379 (5page)
- DOI
- 10.3746/pnf.2020.25.4.375
이용수
초록· 키워드
오류제보하기
There has been a dynamic progression in the study of purple sweet potatoes, particularly in regard to their antioxidant compounds, such as anthocyanins. Antioxidants can reduce oxidative stress due to hyperglycemia, therefore research into the protective effects of hyperglycemia is essential. This study was conducted to investigate the protective effects of anthocyanin extracts from purple sweet potatoes on blood malondialdehyde (MDA) levels, liver and renal activity, and blood pressure in hyperglycemic rats. Anthocyanin from purple sweet potato (APSP) was extracted with ethanol-citric acid 3% solvent. Twenty-four rats were split into four experimental groups: (i) healthy rats; (ii) hyperglycemic rats without anthocyanin treatment; (iii) hyperglycemic rats treated with APSP extract at a dose of 50 mg/kg; and (iv) hyperglycemic rats treated with APSP extract at a dose of 100 mg/kg. Rats received treatment for 35 days. The results showed that consumption of APSP significantly reduced levels of MDA in the blood, and liver and renal systems. APSP could reduce the urea and creatinine levels, which are indicative of improved renal function. In addition, APSP could decrease serum glutamate oxalacetate transaminase and serum glutamate pyruvate transaminase levels, indicative of protective activity of the extract on liver, and decrease systolic blood pressure. Accordingly, it was concluded that APSP could be developed as a functional food for treatment of diabetes.
목차
ABSTRACT
INTRODUCTION
MATERIALS AND METHODS
RESULTS AND DISCUSSION
REFERENCES
참고문헌 (39)
참고문헌 신청
Abdullah KM / 2018 / Therapeutic effect of vitamin B3 on hyperglycemia, oxidative stress and DNA damage in alloxan induced diabetic rat model / Biomed Pharmacother 105:1223~1231
Alezandro MR / 2013 / Jaboticaba (Myrciaria jaboticaba (Vell.) Berg), a Brazilian grape-like fruit, improves plasma lipid profile in streptozotocin-mediated oxidative stress in diabetic rats / Food Res Int. 54:650~659
Alli K / 2017 / Antidiabetic activity of the methanolic extract of the leaves of Basella rubra L. against alloxan induced diabetes in albino rats / World J Pharm Pharm Sci. 6:1295~1308
Amaya-Cruz DM / 2015 / Juice by-products as a source of dietary fibre and antioxidants and their effect on hepatic steatosis / J Funct Foods 17:93~102
Chen YF / 2016 / Purple rice anthocyanin extract protects cardiac function in STZ-induced diabetes rat hearts by inhibiting cardiac hypertrophy and fibrosis / J Nutr Biochem 31:98~105
Alezandro MR / 2013 / Jaboticaba (Myrciaria jaboticaba (Vell.) Berg), a Brazilian grape-like fruit, improves plasma lipid profile in streptozotocin-mediated oxidative stress in diabetic rats / Food Res Int. 54:650~659
Alli K / 2017 / Antidiabetic activity of the methanolic extract of the leaves of Basella rubra L. against alloxan induced diabetes in albino rats / World J Pharm Pharm Sci. 6:1295~1308
Amaya-Cruz DM / 2015 / Juice by-products as a source of dietary fibre and antioxidants and their effect on hepatic steatosis / J Funct Foods 17:93~102
Chen YF / 2016 / Purple rice anthocyanin extract protects cardiac function in STZ-induced diabetes rat hearts by inhibiting cardiac hypertrophy and fibrosis / J Nutr Biochem 31:98~105
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