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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2010.1
- 수록면
- 746 - 751 (6page)
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초록· 키워드
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As part of an ongoing search for natural plants with antioxidant compounds by measuring the radical-scavenging effect on DPPH (1,1-diphenyl-2-picrylbydrazyl), a total extract of the whole plant of Actinostemma lobatum (Cucurbitaceae) was found to show potent antioxidant activity. Subsequent activity-guided fractionation of the methanolic extract led to the isolation of eight compounds: actinostemmoside C (1), kaempferol-3-O-${\alpha}$-L-rhamnopyranosyl ($1{\rightarrow}6$)-${\beta}$-D-glucopyranoside (2), quercetin-3-O-${\beta}$-L-rhamnopyranosyl ($1{\rightarrow}6$)-${\beta}$-D-glucopyranoside (3), quercetin-3-O-${\beta}$-D-glucopyranoside (4), kaempferol (5), quercetin (6), lobatoside C (7), and lobatoside B (8). Their structures were elucidated using spectroscopic studies. Compounds 2, 4, 5, and 6 were isolated for the first time from this plant. Compounds 2-4 and 6 showed significant antioxidative effects during the DPPH-free radical-scavenging test and the superoxide quenching activity test.
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