지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2008.1
- 수록면
- 223 - 226 (4page)
이용수
초록· 키워드
오류제보하기
We introduce a computational approach for analysis of glycosylation in Post-PKS tailoring steps. It is a computational method to predict the deoxysugar biosynthesis unit pathway and the substrate specificity of glycosyltransferases involved in the glycosylation of polyketides. In this work, a directed and weighted graph is introduced to represent and predict the deoxysugar biosynthesis unit pathway. In addition, a homology based gene clustering method is used to predict the substrate specificity of glycosyltransferases. It is useful for the rational design of polyketide natural products, which leads to in silico drug discovery.
목차
등록된 정보가 없습니다.
참고문헌 (6)
참고문헌 신청
Altschul, S.F. / 1990 / Basic local alignment search tool / J. Mol. Biol 213:403~410
Hopwood, D.A. / 1990 / Molecular genetics of polyketides and its comparison with Fatty acid biosynthesis / Annu. Rev. Genet 24:37~66
Carbohydrate Active Enzymes database site
Rix, U / 2002 / Modification of post-PKS tailoring steps through combinatorial biosynthesis / Nat. Prod. Rep 19:542~580
Staunton, J / 2001 / Polyketide biosynthesis: a millennium review / Nat. Prod. Rep 18:380~416
Hopwood, D.A. / 1990 / Molecular genetics of polyketides and its comparison with Fatty acid biosynthesis / Annu. Rev. Genet 24:37~66
Carbohydrate Active Enzymes database site
Rix, U / 2002 / Modification of post-PKS tailoring steps through combinatorial biosynthesis / Nat. Prod. Rep 19:542~580
Staunton, J / 2001 / Polyketide biosynthesis: a millennium review / Nat. Prod. Rep 18:380~416
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Computational System for the Analysis of Post-PKS Glycosylation Step
한국생명과학회 심포지움
2008 .10
-
Computational Approach for Biosynthetic Engineering of Post-PKS Tailoring Enzymes
Genomics & informatics
2008 .01
-
Discovery and Molecular Engineering of Sugar-containing Natural ProductBiosynthetic Pathways in Actinomycetes
Journal of Microbiology and Biotechnology
2007 .01
-
Engineering the deoxysugar moiety of polyketides in Streptomyces venezuelae
한국당과학회 학술대회
2006 .01
-
Engineering of Glycosylation and Secretion Pathway in Yeast for Production of Therapeutic Enzymes
한국미생물학회 학술대회논문집
2013 .05
-
Glycosylation 분석을 위한 질량분석기 원리와 응용
한국미생물학회 학술대회논문집
2014 .04
-
Rapid and Simple Detection of Protein Glycosylation using Nanoparticle-based Energy Transfer
한국당과학회 학술대회
2006 .01
-
당뇨 KK마우스에서 비타민 E 보강식이가 신장 당화단백질 생성에 미치는 영향
한국영양학회지
1998 .07
-
The Role of a Second Protein (DesVIII) in Glycosylation for the Biosynthesis of Hybrid Macrolide Antibiotics in Streptomyces Venezuelae
Journal of Microbiology and Biotechnology
2005 .01
-
Glycosylation of Small Molecules: Synthesis of Flavonoid Glycosides
한국미생물학회 학술대회논문집
2013 .05
-
Possible Negative Effect of Pigmentation on Biosynthesis of Polyketide Mycotoxin Zearalenone in Gibberella zeae
Journal of Microbiology and Biotechnology
2006 .01
-
Development of an Analysis Program of Type I Polyketide Synthase Gene Clusters Using Homology Search and Profile Hidden Markov Model
Journal of Microbiology and Biotechnology
2009 .01
-
Alteration of Mucin Glycosylation in Airway Diseases
한국당과학회 학술대회
2006 .01
-
중앙값을 이용한 Cpk에 대한 연구
Journal of The Korean Data Analysis Society
2009 .01
-
Polyketide 이차대사물질의 생합성
생명과학회지
2002 .10
-
IFNImmunosuppression of xenograft rejection in porcine kidney PK15 cells by porcine IL-18
Experimental and Molecular Medicine
2006 .01
-
Role of a Putative N-Glycosylation Site in Bovine Retinal Cyclic Nucleotide-Gated Channel
한국생물물리학회 학술발표회
1997 .01
-
Modification of HA Glycosylation for Better Immunogenicity of Avian Influenza H7N9 Vaccine
한국미생물학회 학술대회논문집
2018 .04
-
Self-reciprocal polynomials with related maximal zeros
대한수학회보
2013 .01
-
Detection of Novel Polyketide Synthase Genes in Sorangium cellulosum Isolated in Korea
한국미생물·생명공학회지
2010 .01
이 논문의 저자 정보
최근 본 자료
댓글(0)
0