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논문 기본 정보
- 자료유형
- 학술대회자료
- 저자정보
- 저널정보
- 대한약학회 대한약학회 학술대회 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2-2
- 발행연도
- 2003.1
- 수록면
- 961 - 961 (1page)
이용수
이 논문의 연구 히스토리 (2)
2003
Lisophosphatidic Acid Inhibits Melanocyte Proliferation via Cell Cycle Arrest
Kim
,
Dong-Seok
,
Pa
외 14명
Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea
2003.01
학술저널
Lysophosphatidic acid Inhibits Melanocyte Proliferation via Cell Cycle Arrest
Kim
,
Dong-Seok
,
Pa
외 9명
대한약학회 학술대회
2003.01
학술대회자료
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초록· 키워드
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Lysophosphatidic acid (LPA) is a well-known mitogen in various cell types. However, we were surprised to find that LPA inhibits melanocyte proliferation. Thus, we further investigated the possible signaling pathways involved in melanocyte growth inhibition. We first examined the regulation of the three major subfamilies of mitogen-activated protein (MAP) kinases and of the Akt pathway by LPA. The activations of extracellular signal-regulated protein kinase (ERK) and c-Jun N-terminal kinase (JNK) were observed in concert with the inhibition of melanocyte proliferation by LPA, whereas p38 MAP kinase and Akt were not influenced by LPA. (omitted)
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Adipose-Derived Stem Cell Coculturing Stimulates Integrin-Mediated Extracellular Matrix Adhesion of Melanocytes by Upregulating Growth Factors
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