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- 대한약학회 대한약학회 학술대회 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2-2
- 발행연도
- 2003.1
- 수록면
- 1,862 - 1,862 (1page)
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PPARs (peroxisome proliferator activated receptors) are member of nuclear hormone receptors superfamily. Activations of PPARs upon binding with ligands modulate glucose metabolite, differentiation of adipocyte, inflammation response, and so on. Thiazolidinedione analog is one of the potential antidiabetic drug that binds and activates PPAR selectively and enhances insulin sensitivity. In an effort to develop novel and effective antidiabetic thiazolidindione analogs, we have synthesized tetrahydroquinoline and para-substituted benzene-linked thiazolidinedione analogs by coupling reaction of the hydrophobic segments with hydroxybenzylthiazolidinedione.
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Synthesis of thiazolidinedione analogs
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Synthesis and Biological Activity of [[(Heterocycloamino)alkoxy] benzyl]-2,4-thiazolidinediones as $PPAR_\gamma$ Agonists
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Synthesis and biological activity of novel substituted pyridines and purines containing 2,4-thiazolidinedione
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Modulation of the Transcriptional Activity of Peroxisome Proliferator-Activated Receptor Gamma by Protein-Protein Interactions and Post-Translational Modifications
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Peroxisome Proliferator-Activated Receptor (PPAR) α/γ 작용제
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Expression of Peroxisome Proliferator-Activated Receptor Gamma in Helicobacter Pylori-associated Mouse Gastric Cancer Tissue and Human Gastric Epithelial Cells.
한국수의병리학회 학술발표논문집
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Design and Synthesis of Novel Antidiabetic Agents
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A Novel PPARγ Agonist, SP1818, Shows Different Coactivator Profile with Rosiglitazone
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Repression of PPARγ Activity on Adipogenesis by 17β-estradiol in Differentiated 3T3-L1 Cell
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Peroxisome Proliferator-activated Receptor γ Is Not Associated with Adipogenesis in Female Mice
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Fenofibrate, a peroxisome proliferator-activated receptor α-agonist, blocks lipopolysaccharide-induced inflammatory pathways in mouse liver
Annals of Hepato-Biliary-Pancreatic Surgery
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Peroxisome Proliferator-Activated $Receptor-{\gamma}$ 2 $(PPAR{\gamma}2)$ Pro12Ala (P12A) 유전자 다형성이 한국여성의 체지방분포에 미치는 영향
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치수세포에서 PPARγ의 항 염증작용에 관한 연구
Restorative Dentistry and Endodontics
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Synthesis and Biological Activity of Benzoxazole Containing Thiazolidinedione Derivatives
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PPAR-γ 작용제의 치료적 역할
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Two Synthetic Ligands for Peroxisome Proliferator-Activated Receptor γ
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제 2형 당뇨병 및 당뇨 합병증의 발생과 Peroxisome Proliferator-Activated Receptor-γ2 C161T 유전자 다형성과의 관계
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Ubiquitination of p53 is Involved in Troglitazone Induced Apoptosis in Cervical Cancer Cells
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Synthesis of Polymeric Thiazolidinedione and Fibrate Conjugates
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Association of the PPAR-γ Gene with Altered Glucose Levels and Psychosis Profile in Schizophrenia Patients Exposed to Antipsychotics
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