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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한약학회 Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea 제27권 제11호
- 발행연도
- 2004.1
- 수록면
- 1,099 - 1,105 (7page)
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초록· 키워드
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The peroxisome proliferator-activated receptors (PPARs) are a primary regulator of lipid metabolism. Potency for activation of PPAR$\gamma$, one of a subfamily of PPARs, particularly mirrors glucose lowering activity. We prepared thiazolidinediones featuring benzoxazole moiety for subtype selective PPAR$\gamma$ activators. 5-[4-[2-(Benzoxazol-2-yl-alkylamino)ethoxy]benzyl]thiazolidine-2,4-diones have been prepared by Mitsunobu reaction of benzoxazolylalkylaminoethanol 8 and hydroxybenzylthiazolidinedione 6 and their activities were evaluated. Most compounds tested were identified as potent PPAR$\gamma$ agonists.
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Synthesis and Biological Activity of [[(Heterocycloamino)alkoxy] benzyl]-2,4-thiazolidinediones as $PPAR_\gamma$ Agonists
Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea
2006 .01
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Synthesis and Biological Activity of 5-{4-[2-(Methyl-p-substituted phenylamino)ethoxy]benzyl}thiazolidine-2,4-diones
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Synthesis of thiazolidinedione analogs
대한약학회 학술대회
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Synthesis and Study of Antibacterial and Antifungal Activities of Novel 2-[[(Benzoxazole/benzimidazole-2-yl)sulfanyl]acetylamino]thiazoles
Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea
2004 .01
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Synthesis of TZD Analogs as PPAR${\gamma}$ Specific Ligands
대한약학회 학술대회
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Design and Synthesis of Novel Antidiabetic Agents
Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea
2005 .01
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HANTZSCH DIHYDROPYRIDINE: AN EFFECTIVE AND CONVENIENT REGIOSELECTIVE REDUCING AGENT FOR 5-BENZYLIDENE-2,4- THIAZOLIDINEDIONE DERIVATIVES
대한약학회 학술대회
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Short Insulin Tolerance Test Can Determine the Effects of Thiazolidinediones Treatment in Type 2 Diabetes
Yonsei Medical Journal
2008 .01
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Synthesis and biological activity of novel substituted pyridines and purines containing 2,4-thiazolidinedione
대한약학회 학술대회
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Synthesis and Three-dimensional Qualitative Structure Selectivity Relationship of 3,5-Disubstituted-2,4- Thiazolidinedione Derivatives As COX2 Inhibitors
Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea
2007 .01
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Modulation of the Transcriptional Activity of Peroxisome Proliferator-Activated Receptor Gamma by Protein-Protein Interactions and Post-Translational Modifications
Yonsei Medical Journal
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A Novel PPARγ Agonist, SP1818, Shows Different Coactivator Profile with Rosiglitazone
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Isolation of the ppar-${\gamma}$ ligands from the stem of the Zanthoxylum Schinifolium and their structure activity relationships
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Peroxisome Proliferator-Activated Receptor (PPAR) α/γ 작용제
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Repression of PPARγ Activity on Adipogenesis by 17β-estradiol in Differentiated 3T3-L1 Cell
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Discovery of a Novel $PPAR{\gamma}$ Agonist, KR62980 with New Indication of Osteoporosis Treatment
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PPAR-γ 작용제의 치료적 역할
Korean Journal of Family Medicine
2006 .01
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Synthesis of Polymeric Thiazolidinedione and Fibrate Conjugates
Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea
2008 .01
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Synthesis of Polymeric Thiazolidinediones and L-Ascorbic Acid Towards the Development of Insulin-Sensitizer
Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea
2005 .01
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Expression of Peroxisome Proliferator-Activated Receptor Gamma in Helicobacter Pylori-associated Mouse Gastric Cancer Tissue and Human Gastric Epithelial Cells.
한국수의병리학회 학술발표논문집
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