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논문 기본 정보
- 자료유형
- 학술대회자료
- 저자정보
- 발행연도
- 1994.1
- 수록면
- 263 - 263 (1page)
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초록· 키워드
오류제보하기
Annexin I is a member of the in family of calcium dependent phospholipid banding proteins and is an in vitro phospholipase $A_2$ (PLA$_2$) inhibitor. The mechanism of PLA$_2$ inhibition by annexin I is still ambiguous. The structure of annexin I was studied at the atomic level by using nuclear magnetic resonance (NMR), circular dichrotsm (CD) and fluorescence spectroscopy. Recombinant human annexin I and N-terminally truncated annexin I (1-31 deleted: d-annexin I) were purified and their NMR spectra were compared. The NMR spectra of the two were similar. When $Ca^{2+}$ ion added to annexin I ad d-annexin I, peak broadening occurred, but no significant spectroscopic change was observed. When porcine pancreatic PLA$_2$ was added to deuterium labeled annexin I, an interaction of annexin I with PLA$_2$ was observed as indicated by the disappearance and shift of several peaks in the NMR spectrum. This result supports a protein-protein interaction mechanism for PLA$_2$ inhibition by annexin I.I.
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NMR Studies on the Structure of Human Annexin I
한국응용약물학회 춘계학술발표논문집
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Expression of Annexin A3 in Gastric Cancer and its Correlation with Proliferation and Apoptosis
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Ginsenoside compound K inhibits nuclear factor-kappa B by targeting Annexin A2
Journal of Ginseng Research
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Annexin A5 as a New Potential Biomarker for Cisplatin-Induced Toxicity in Human Kidney Epithelial Cells
Biomolecules & Therapeutics(구 응용약물학회지)
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자궁경부암에서 Annexin I 및 Thymosin β4의 발현에 관한 연구
Obstetrics & Gynecology Science
2008 .01
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Role of Annexin A5 on Mitochondria-Dependent Apoptosis Induced by Tetramethoxystilbene in Human Breast Cancer Cells
Biomolecules & Therapeutics(구 응용약물학회지)
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Annexin A2 and CD105 Expression in Pancreatic Ductal Adenocarcinoma is Associated with Tumor Recurrence and Prognosis
Asian Pacific journal of cancer prevention : APJCP
2014 .01
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Auranofin Suppresses Plasminogen Activator Inhibitor-2 Expression through Annexin A5 Induction in Human Prostate Cancer Cells
Biomolecules & Therapeutics(구 응용약물학회지)
2017 .01
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세포고사의 핵의학영상
대한핵의학회지
2004 .01
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NMR Studies on the Structure of Human Annexin I
한국응용약물학회 춘계학술발표논문집
1997 .01
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Regulatory Mechanisms of Annexin-Induced Chemotherapy Resistance in Cisplatin Resistant Lung Adenocarcinoma
Asian Pacific journal of cancer prevention : APJCP
2014 .01
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Efficacy of Annexin A1 Immunostaining in Bone Marrow for the Diagnosis of Hairy Cell Leukemia
Laboratory Medicine Online
2019 .01
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Tc-99m Annexin V Imaging and Apoptosis Staining in Rabbit Model of Osteoarthritis
대한핵의학회 학술대회
2004 .01
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Neuroprotective Effect of Resveratrol on Acute Brain Ischemia Reperfusion Injury by Measuring Annexin V, p53, Bcl-2 Levels in Rats
대한신경외과학회지
2015 .01
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세포고사 영상화를 위한 Tc-99m-HYNIC-Annexin V의 제조 및 생체분포
대한핵의학회 학술대회
2003 .01
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In vivo prediction of anti-tumor effect of 3-bromopyruvate in Hepatocellular Carcinoma using Tc-99m labeled Annexin-V imaging
대한핵의학회 학술대회
2005 .01
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Targeted Ultrasound Imaging of Apoptosis with Annexin A5 Microbubbles in Acute Doxorubicin-Induced Cardiotoxicity
Journal of Cardiovascular Imaging
2010 .01
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OVCAR-3 세포주에서 Annexin V, Propium Iodide와Cytokeratin 염색에 의한 고사세포의 측정
Obstetrics & Gynecology Science
2003 .01
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Imaging Myocardial Ischemia and Reperfusion Injury via Cy5.5-Annexin V
Nuclear medicine and molecular imaging : NMMI
2012 .01
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