지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
이용수
초록· 키워드
오류제보하기
Detailed structural and molecular imaging of intact organs has incurred academic interest because the associated technique is expected to provide innovative information for biological investigation and pathological diagnosis. The conventional methods for volume imaging include reconstruction of images obtained from serially sectioned tissues. This approach requires intense manual work which involves inevitable uncertainty and much time to assemble the whole image of a target organ. Recently, effective tissue clearing techniques including CLARITY and ACT-PRESTO have been reported that enables visualization of molecularly labeled structures within intact organs in three dimensions. The central principle of the methods is transformation of intact tissue into an optically transpicuous and macromolecule permeable state without loss of intrinsic structural integrity. The rapidly evolving protocols enable morphological analysis and molecular labeling of normal and pathological characteristics in large assembled biological systems with single-cell resolution. The deep tissue volume imaging will provide fundamental information about mutual interaction among adjacent structures such as connectivity of neural circuits; meso-connectome and clinically significant structural alterations according to pathologic mechanisms or treatment procedures.
목차
등록된 정보가 없습니다.
참고문헌 (0)
참고문헌 신청함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Three-Dimensional Approaches in Histopathological Tissue Clearing System
대한임상검사과학회지
2020 .01
-
Assessment of The Accuracy of The MR Abdominal Adipose Tissue Volumetry using 3D Gradient Dual Echo 2-Point DIXON Technique using CT as Reference
Journal of Magnetics
2016 .12
-
Current Status on Bio-Spintronics Researches : From molecular diagnosis to Tissue engineering
한국자기학회 학술연구발표회 논문개요집
2018 .03
-
Analysis of KAP1 expression patterns and human endogenous retrovirus Env proteins in ovarian cancer
Genes & Genomics
2020 .01
-
Salmonella Single-cell Dynamics in Complex Host Tissues
한국미생물학회 학술대회논문집
2016 .04
-
Single-Cell Molecular Barcoding to Decode Multimodal Information Defining Cell States
Molecules and Cells
2023 .02
-
비만에서 adipose tissue 호르몬에 의한 metabolic signaling
생명과학회지
2023 .03
-
Mapping Cellular Coordinates through Advances in Spatial Transcriptomics Technology
Molecules and Cells
2020 .01
-
Application of Terahertz Spectroscopy and Imaging in the Diagnosis of Prostate Cancer
Current Optics and Photonics
2020 .02
-
Microbiota of Breast Tissue and Its Potential Association with Regional Recurrence of Breast Cancer in Korean Women
Journal of Microbiology and Biotechnology
2021 .12
-
Light-Microscopy-Based Sparse Neural Circuit Reconstruction: Array Tomography and Other Methods
한국현미경학회지
2016 .12
-
Distinct cellular composition between normal surgical margins and tumor tissues in oral squamous cell carcinoma
Genes & Genomics
2023 .06
-
Molecular tools for recording and intervention of neuronal activity
Molecules and Cells
2024 .01
-
Classification of Midinfrared Spectra of Colon Cancer Tissue Using a Convolutional Neural Network
Current Optics and Photonics
2022 .02
-
Sensory nerve and neuropeptide diversity in adipose tissues
Molecules and Cells
2024 .01
-
Agonist (P1) Antibody Converts Stem Cells into Migrating Beta-Like Cells in Pancreatic Islets
Journal of Microbiology and Biotechnology
2022 .12
-
Circulating Tumor DNA in a Breast Cancer Patient's Plasma Represents Driver Alterations in the Tumor Tissue
Genomics & informatics
2017 .01
-
E3 ligase BRUTUS Is a Negative Regulator for the Cellular Energy Level and the Expression of Energy Metabolism-Related Genes Encoded by Two Organellar Genomes in Leaf Tissues
Molecules and Cells
2022 .05
-
Super-resolution Microscopy with Adaptive Optics for Volumetric Imaging
Current Optics and Photonics
2022 .12
-
Advances and Applications of Mass Spectrometry Imaging in Neuroscience: An Overview
Mass Spectrometry Letters
2023 .09
이 논문의 저자 정보
최근 본 자료
댓글(0)
0