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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2024.1
- 수록면
- 1 - 14 (14page)
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Both brown and white adipose tissues (BAT/WAT) are innervated by the peripheral nervous system, including efferent sympa thetic nerves that communicate from the brain/central nervous system out to the tissue, and afferent sensory nerves thatcommunicate from the tissue back to the brain and locally release neuropeptides to the tissue upon stimulation. This bidirec tional neural communication is important for energy balance and metabolic control, as well as maintaining adipose tissue healththrough processes like browning (development of metabolically healthy brown adipocytes in WAT), thermogenesis, lipolysis,and adipogenesis. Decades of sensory nerve denervation studies have demonstrated the particular importance of adiposesensory nerves for brown adipose tissue and WAT functions, but far less is known about the tissue’s sensory innervationcompared to the better-studied sympathetic nerves and their neurotransmitter norepinephrine. In this review, we cover what isknown and not yet known about sensory nerve activities in adipose, focusing on their effector neuropeptide actions in the tissue.
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