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논문 기본 정보

자료유형
학술저널
저자정보
In Gyoung Kim (Korea Photonics Technology Institute) Changho Lee (Chonnam National University) Hyeon Sik Kim (Korea Photonics Technology Institute) Sung Chul Lim (Chosun University Hospital) Jae Sung Ahn (Korea Photonics Technology Institute)
저널정보
한국광학회 Current Optics and Photonics Current Optics and Photonics Vol.6 No.1
발행연도
2022.2
수록면
92 - 103 (12page)

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초록· 키워드

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The development of midinfrared (mid-IR) quantum cascade lasers (QCLs) has enabled rapid high-contrast measurement of the mid-IR spectra of biological tissues. Several studies have compared the differences between the mid-IR spectra of colon cancer and noncancerous colon tissues. Most mid-IR spectrum classification studies have been proposed as machine-learning-based algorithms, but this results in deviations depending on the initial data and threshold values. We aim to develop a process for classifying colon cancer and noncancerous colon tissues through a deep-learning-based convolutional-neural-network (CNN) model. First, we image the midinfrared spectrum for the CNN model, an image-based deep-learning (DL) algorithm. Then, it is trained with the CNN algorithm and the classification ratio is evaluated using the test data. When the tissue microarray (TMA) and routine pathological slide are tested, the ML-based support-vector-machine (SVM) model produces biased results, whereas we confirm that the CNN model classifies colon cancer and noncancerous colon tissues. These results demonstrate that the CNN model using midinfrared-spectrum images is effective at classifying colon cancer tissue and noncancerous colon tissue, and not only submillimeter-sized TMA but also routine colon cancer tissue samples a few tens of millimeters in size.

목차

Ⅰ. INTRODUCTION
Ⅱ. METHODS
Ⅲ. RESULTS
Ⅳ. DISCUSSION
Ⅴ. CONCLUSION
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