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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2016.1
- 수록면
- 127 - 133 (7page)
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Purpose: To demonstrate the clinical characteristics of juvenile-onset open angle glaucoma (JOAG) and to evaluatethe prognostic factors for visual field (VF) progression in eyes with JOAG.
Methods: The medical records of 125 eyes of 72 patients with JOAG were analyzed retrospectively. At leastfour reliable VF tests were required to determine the VF progression, and the progression was defined usingthe modified Anderson criteria. Comparisons in clinical manifestations among groups were performed usingindependent t-test, and generalized estimating equations were also conducted.
Results: The mean follow-up duration was 94.4 ± 50.5 months. Patients with JOAG showed a male preponderance(64%), myopia (-4.99 ± 4.01 diopters) and a severe elevation of intraocular pressure (35.6 ± 10.8 mmHg).
Forty-two JOAG patients (58%) had complained of symptoms associated with vision and pain; however, onethirdpresented with no definite symptoms. Fifty-seven patients were diagnosed with JOAG in both eyes, andthey were significantly older (p = 0.039) and had a greater family history (p = 0.035) than patients with unilateralJOAG. The progression group exhibited a significantly higher intraocular pressure at the last visit (p = 0.023)than the non-progression group.
Conclusions: Because patients with considerable JOAG had no definite symptoms, periodic eye examinationsare needed. To prevent the VF’s progression, JOAG patients may require more careful management of intraocularpressure.
목차
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참고문헌 (23)
참고문헌 신청
Dielemans I / 1994 / The prevalence of primary open-angle glaucoma in a population-based study in The Netherlands: the Rotterdam Study / Ophthalmology 101:1851~1855
Iwase A / 2004 / The prevalence of primary open-angle glaucoma in Japanese: the Tajimi Study / Ophthalmology 111:1641~1648
Wang YX / 2010 / Prevalence of glaucoma in North China: the Beijing Eye Study / Am J Ophthalmol 150:917~924
Johnson AT / 1993 / Clinical features and linkage analysis of a family with autosomal dominant juvenile glaucoma / Ophthalmology 100:524~529
Wiggs JL / 1994 / Genetic linkage of autosomal dominant juvenile glaucoma to 1q21-q31 in three affected pedigrees / Genomics 21:299~303
Iwase A / 2004 / The prevalence of primary open-angle glaucoma in Japanese: the Tajimi Study / Ophthalmology 111:1641~1648
Wang YX / 2010 / Prevalence of glaucoma in North China: the Beijing Eye Study / Am J Ophthalmol 150:917~924
Johnson AT / 1993 / Clinical features and linkage analysis of a family with autosomal dominant juvenile glaucoma / Ophthalmology 100:524~529
Wiggs JL / 1994 / Genetic linkage of autosomal dominant juvenile glaucoma to 1q21-q31 in three affected pedigrees / Genomics 21:299~303
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