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자료유형
학술저널
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대한안과학회 Korean Journal of Ophthalmology Korean Journal of Ophthalmology 제34권 제1호
발행연도
2020.1
수록면
56 - 66 (11page)

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Purpose: To categorize the structural progression pattern of glaucoma, as detected by optical coherence tomographyguided progression analysis, with respect to the peripapillary retinal nerve fiber layer (RNFL) andmacular ganglion cell-inner plexiform layer (GCIPL). Methods: One hundred sixty-four eyes with primary open-angle glaucoma were studied. The structural progressionpattern evaluated by optical coherence tomography guided progression analysis was classified usinghierarchical cluster analysis. The clinical parameters, patterns of structural progression, and visual field (VF)changes were compared among the groups. Results: Three groups were included: stable, progressive peripapillary RNFL thinning without macular GCIPLinvolvement, and progressive thinning of both the peripapillary RNFL and macular GCIPL. The third group,those with progressive peripapillary RNFL and macular GCIPL thinning, showed more progressive peripapillaryRNFL thinning in the inferotemporal area and VF progression in the parafoveal area. Conversely, the 12and 6 o’clock areas were the most common locations of progressive peripapillary RNFL thinning in the groupwithout macular GCIPL involvement. Conclusions: Structural progression patterns of glaucoma can be categorized into three groups. The locationof progressive peripapillary RNFL thinning is associated with progressive macular GCIPL thinning and patternof VF changes in the affected area. Our results indicate that the use of only macular GCIPL analysis is inadequatefor analyzing the structural progression of glaucoma.

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