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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 한국미생물생명공학회 Journal of Microbiology and Biotechnology Journal of Microbiology and Biotechnology 제27권 제11호
- 발행연도
- 2017.1
- 수록면
- 1,961 - 1,970 (10page)
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초록· 키워드
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Lespedeza cuneata G. Don is a traditional herb that has been associated with multiple biological activities. In this study, we investigated the antioxidative/antiaging activities and performed an active component analysis of the non-fermented and fermented (using Lactobacillus pentosus) extracts of Lespedeza cuneata G. Don. The antioxidative activities of the fermented extract were higher than those of non-fermented extracts. The elastase inhibitory activity, inhibitory effects on UV-induced MMP-1 expression, and ability to promote type I procollagen synthesis were investigated in Hs68 human fibroblasts cells. These tests also revealed that the fermented extract had increased antiaging activities compared with the non-fermented extract.
A component analysis of the ethyl acetate fractions of non-fermented and fermented extracts was performed using TLC, HPLC, and LC/ESI-MS/MS to observe changes in the components before and after fermentation. Six components that were different before and after fermentation were investigated. It was thought that kaempferol and quercetin were converted from kaempferol glucosides and quercetin glucosides, respectively, via bioconversion with the fermentation strain. These results indicate that the fermented extract of L. cuneata G. Don has potential for use as a natural cosmetic material with antioxidative and antiaging effects.
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참고문헌 (23)
참고문헌 신청
Huynh TN / 2016 / Extraction and bioconversion of kaempferol metabolites from cauliflower outer leaves through fungal fermentation / Biochem. Eng. J 116 : 27 ~ 33
Im AR / 2014 / Anti-wrinkle effects of fermented and non-fermented Cyclopia intermedia in hairless mice / BMC Complement. Altern. Med 14 : 424 ~ 429
Kammeyer A / 2015 / Oxidation events and skin aging / Ageing Res. Rev 21 : 16 ~ 29
Kim M / 2015 / Youngiasides A and C isolated from Youngia denticulatum inhibit UVBinduced MMP expression and promote type I procollagen production via repression of MAPK/AP-
Okabe Y / 2011 / Higher bioavailability of isoflavones after a single ingestion of aglycone-rich fermented soybeans compared with glucoside-rich nonfermented soybeans in Japa
Im AR / 2014 / Anti-wrinkle effects of fermented and non-fermented Cyclopia intermedia in hairless mice / BMC Complement. Altern. Med 14 : 424 ~ 429
Kammeyer A / 2015 / Oxidation events and skin aging / Ageing Res. Rev 21 : 16 ~ 29
Kim M / 2015 / Youngiasides A and C isolated from Youngia denticulatum inhibit UVBinduced MMP expression and promote type I procollagen production via repression of MAPK/AP-
Okabe Y / 2011 / Higher bioavailability of isoflavones after a single ingestion of aglycone-rich fermented soybeans compared with glucoside-rich nonfermented soybeans in Japa
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