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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 한국미생물생명공학회 Journal of Microbiology and Biotechnology Journal of Microbiology and Biotechnology 제16권 제4호
- 발행연도
- 2006.1
- 수록면
- 584 - 589 (6page)
이용수
초록· 키워드
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Bifidobacteria has been suggested to exert healthpromoting effects on the host by maintaining microbial floraand modulating imune functions in the human intestine. Weassessed modulatory effects of the diferent cel fractions ofBifidobacterium sp. BGN4 on macrophage cells and otherimmune cells from the spleen and Peyer’s patches (PP) ofmouse. Cell free extracts (CFE) of the BGN4 fractions inducedand increased the phagocytic activity more effectively thanother fractions in the mouse peritoneal cells. Nitric oxide(NO) production was significantly reduced by both the celwalls (CW) and CFE in the cultured cells from the spleen andPP. The production of interleukin-6 (IL-6) and interleukin-10(IL-10) was eminent in the spleen cells treated with experimentalBGN4 cel fractions. However, in the PP cels, IL-6 wasslightly decreased by the treatment with the whole cell (WC)treatment with the CW and CFE. These results sugest thatdiferent types of bifidobacterial cel fractions may havediferential imunomodulatory activities depending on theirlocation within the host immune system.
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등록된 정보가 없습니다.
참고문헌 (20)
참고문헌 신청
Bezkorovany, A / 1989 / Ecology of bifidobacteria (in Biochemistry and Physiology of Bifidobacteria) / CRC press, Florida, U.S.A. : 29 ~ 72
Dong, W / 1994 / Elevated gene expression and production of interleukins 2, 4, 5 and 6 during exposure to vomitoxin (deoxynivalenol) and cycloheximide in the EL-4 thymoma / T
Fukuo, K / 1995 / Nitric oxide mediates cytotoxicity and basic fibroblast growth factor release in cultured vascular smooth muscle cells. A possible mechanism of neo vascular
Fuseler, J. M / 1997 / Cytokine and nitric oxide production in the acute phase of bacterial cell wall-induced arthritis / Inflammation 21 : 113 ~ 131
Hatcher, G. E / 1993 / Augmentation of macrophage phagocytic activity by cell free extracts of selected lactic acid-producing bacteria / J. Dairy Sci. 76 : 2485 ~ 2492
Dong, W / 1994 / Elevated gene expression and production of interleukins 2, 4, 5 and 6 during exposure to vomitoxin (deoxynivalenol) and cycloheximide in the EL-4 thymoma / T
Fukuo, K / 1995 / Nitric oxide mediates cytotoxicity and basic fibroblast growth factor release in cultured vascular smooth muscle cells. A possible mechanism of neo vascular
Fuseler, J. M / 1997 / Cytokine and nitric oxide production in the acute phase of bacterial cell wall-induced arthritis / Inflammation 21 : 113 ~ 131
Hatcher, G. E / 1993 / Augmentation of macrophage phagocytic activity by cell free extracts of selected lactic acid-producing bacteria / J. Dairy Sci. 76 : 2485 ~ 2492
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