지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2007.1
- 수록면
- 439 - 449 (11page)
이용수
초록· 키워드
오류제보하기
Neutrophils are also known to acquire the character-istics of dendritic cells (DCs) under the appropriate conditions. In this study, neutrophils were cultivated in vitro in the presence or absence of compounds mod-expression profile of the DC markers. Higher MHC-I, CD80, CD86, CD83, and CD40 expression levels were detected on the surface of the cultured neutrophils for 24 h than on the freshly isolated cells. The annexin V-positive cells showed a higher expression level of the DC markers than the annexin V-negative cells. The population of neutrophils double stained with anexin V and the DC markers increased after being incubated with agonistic anti-Fas Ab. LPS, the anti-apoptotic compound, decreased the CD86 and MHC-I ex-pression levels but 50-60% of the DC marker-positive cells were detected in the annexin V-positive cells. In contrast, CD80, CD86, CD83, and HLA-DR mRNA levels increased in the GM-CSF-treated neutrophils but not in the anti-Fas Ab-treated neutrophils. T cell pro-liferation was inhibited by co-culturing them with an-ti-Fas Ab- or LPS-treated neutrophils at a high neu-ated T cell proliferation was increased by the LPS-treat-ed neutrophils but decreased by the anti-Fas Ab-treat-ed neutrophils. There was a lower level of interferon-γ production in the T cells co-cultured with anti-Fas Ab-treated neutrophils than with the LPS-treated neutrophils. This suggests that apoptotic neutrophils express DC markers on their surface and the difer-ential expression of DC markers might have a detri-detrimental
effect on the immune reaction.
목차
등록된 정보가 없습니다.
참고문헌 (24)
참고문헌 신청
Aleman M / 2005 / In tuberculous pleural effusions, activated neutrophils undergo apoptosis and acquire a dendritic cell-like phenotype 192 : 399 ~ 409
Bliss SK / 2000 / Rapid recruitment of neutrophils containing prestored IL-12 during microbial infection 165 : 4515 ~ 4521
Burg ND / 2001 / The neutrophil: function and regulation in innate and humoral immunity 99 : 7 ~ 17
Clayton AR / 2003 / Dendritic cell uptake of human apoptotic and necrotic neutrophils inhibits CD40, CD80, and CD86 expression and reduces allogeneic T cell responses: releva
Dransfield I / / Hogg N. Neutrophil apoptosis is associated with a reduction in CD16 : 1254 ~ 63
Bliss SK / 2000 / Rapid recruitment of neutrophils containing prestored IL-12 during microbial infection 165 : 4515 ~ 4521
Burg ND / 2001 / The neutrophil: function and regulation in innate and humoral immunity 99 : 7 ~ 17
Clayton AR / 2003 / Dendritic cell uptake of human apoptotic and necrotic neutrophils inhibits CD40, CD80, and CD86 expression and reduces allogeneic T cell responses: releva
Dransfield I / / Hogg N. Neutrophil apoptosis is associated with a reduction in CD16 : 1254 ~ 63
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Neutrophils in Immunity
JOURNAL OF BACTERIOLOGY AND VIROLOGY
2012 .06
-
LFA-1 (CD11a/CD18) and Mac-1 (CD11b/CD18) distinctly regulate neutrophil extravasation through hotspots I and II
Experimental and Molecular Medicine
2019 .01
-
CD43 cross-linking increases the Fas-induced apoptosis through induction of Fas aggregation in Jurkat T-cells
Experimental and Molecular Medicine
2006 .01
-
Der p 1 Inhibits Spontaneous Neutrophil Apoptosis by Cytokine Secretion of Normal and Allergic Lymphocytes
대한임상검사과학회지
2015 .01
-
Selective addition of CXCR3+CCR4-CD4+ Th1 cells enhances generation of cytotoxic T cells by dendritic cells in vitro
Experimental and Molecular Medicine
2009 .01
-
Photodynamically induced endothelial cell injury and neutrophil-like HL-60 adhesion
Journal of photoscience : an international journal officail organ of the korean society of photoscience
2002 .01
-
Suppressive Effect of Der p 2 on Constitutive Neutrophil Apoptosis by Cytokine Secretion of Normal and Allergic Lymphocytes
대한임상검사과학회지
2016 .01
-
Angiostatin Works as Immune Modulatory Molecules via Inhibition of Neutrophil Activation and Migration
JOURNAL OF BACTERIOLOGY AND VIROLOGY
2014 .03
-
프레닐 페놀계 항생제인 4-O-methyl-ascochlorin에 의한 호중구 세포사멸의 유도
생명과학회지
2006 .02
-
Activation of B cells using Schneider 2 cells expressing CD40 ligand for the enhancement of antigen presentation in vitro
Experimental and Molecular Medicine
2005 .01
-
호중구의 자연 세포사멸 및 세포사멸 지연에 대한 Brefeldin A의 영향
생명과학회지
2002 .08
-
Detection of homodimer formation of CD99 throughextracelluar domain using bimolecular fluorescencecomplementation analysis
Experimental and Molecular Medicine
2007 .01
-
CD55, CD59 결핍에 의한 발작성 야간 혈색소뇨증 2예
대한임상검사과학회지
1998 .01
-
Induction of Regulatory Dendritic Cells by Lactobacillus paracasei L9 Prevents Allergic Sensitization to Bovine β-Lactoglobulin in Mice
Journal of Microbiology and Biotechnology
2015 .01
-
Comparison of the Oxidative Burst Signaling Pathways of Plants and Human Neutrophils.
한국식물학회 심포지움
1994 .01
-
House Dust Mite Allergen Inhibits Constitutive Neutrophil Apoptosis by Cytokine Secretion via PAR2/PKC/p38 MAPK Pathway in Allergic Lymphocytes
대한임상검사과학회지
2016 .01
-
Intracellular CD154 Expression Reflects Antigen-specific CD8+ T Cells butShows Less Sensitivity than Intracellular Cytokine and MHC TetramerStaining
Journal of Microbiology and Biotechnology
2007 .01
-
Sorting CD4⁺ T Cells in Blood by Magnetic Nanoparticles Coated with Anti-CD4 Antibody
한국자기학회 학술연구발표회 논문개요집
2007 .05
-
Serine protease 억제제인 4-(2-aminoethyl) benzensulfonylfluoride (AEBSF)에 의한 호중구의 자연 세포사멸의 지연과 수지상 세포로의 전이분화 연구
생명과학회지
2007 .07
이 논문의 저자 정보
최근 본 자료
댓글(0)
0