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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2009.1
- 수록면
- 50 - 59 (10page)
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Objectives : The aim of this study was conducted that CRE (Coptidis Rhizoma Extract) induces apoptosis in YD-10B cells, human oral squamous carcinoma cell line.
Methods : In this study, YD-10B cells were exposed to CRE (0.03-0.30 mg/ml), for 6-24 hours. We measured the effects of CRE on the changes of cell viability and cell membrane, TUNEL assay of CRE-treated YD-10B cell.
Results : In this study, CRE caused a decrease of viability in YD-10B cells, human oral squamous carcinoma cell line. When YD-10B cells were treated with CRE, cells showed dose-dependent manner apoptotic cell death.
Conclusions : These results suggest that CRE may be potential therapeutic approach in the clinical management of oral squamous cell carcinoma.
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참고문헌 (31)
참고문헌 신청
Arbes SJ Jr / 1999 / Factors contributing to the poorer survival of black Americans diagnosed with oral cancer (United states) / Cancer Causes and Control 10 : 513 ~ 523
Bary F / 2002 / Estimates of cancer incidence and mortality in Europe in 1995 / Euro J cancer 38 : 99 ~ 166
Chandu A / 2005 / The assessment of quality of life in atients who have undergone surgery for oral cancer: A preliminary report / Oral Maxillofac Surg 63 : 1606 ~ 1612
Duke RC / 1996 / Cell suicide in health and disease / Sci Am 275 (6) : 80 ~ 87
Elmore S / 2007 / Apoptosis: a review of programmed cell death / Toxicol Pathol 35 (4) : 495 ~ 516
Bary F / 2002 / Estimates of cancer incidence and mortality in Europe in 1995 / Euro J cancer 38 : 99 ~ 166
Chandu A / 2005 / The assessment of quality of life in atients who have undergone surgery for oral cancer: A preliminary report / Oral Maxillofac Surg 63 : 1606 ~ 1612
Duke RC / 1996 / Cell suicide in health and disease / Sci Am 275 (6) : 80 ~ 87
Elmore S / 2007 / Apoptosis: a review of programmed cell death / Toxicol Pathol 35 (4) : 495 ~ 516
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