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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한자기공명의과학회 Investigative Magnetic Resonance Imaging Investigative Magnetic Resonance Imaging 제12권 제2호
- 발행연도
- 2008.1
- 수록면
- 115 - 122 (8page)
이용수
초록· 키워드
오류제보하기
Purpose : To evaluate the correlation between the radiological non-invasive hepatic fibrosis index (RNHFI), as determined by SPIO-enhanced MRI, and the laboratory non-invasive hepatic fibrosis index.
Materials and Methods : Patients (99 total: 61 men and 38 women; mean age: 58 years) who underwent SPIO-enhanced MRI (1.5T) during 5 years included. These patients were subdivided into a liver cirrhosis group (LCG) and a non-liver cirrhosis group (non-LCG). Using PACS view, we measured the RNHFI (mean standard deviation of hepatic signal intensity (SD), noise-corrected coefficient of variation (CV)) of three ROIs in the liver parenchyma by SPIO-enhanced MRI. The laboratory non-invasive hepatic fibrosis index (AST-platelet ratio index (APRI)) of all patients was calculated from the laboratory data. We compared the RNHFI and APRI of LCG with those of
non-LC group using Student’s t-test. A bivariate correlation was performed to
investigate the relationship between the RNHFI and APRI in the LCG.
Results : For the LCG, mean values of SD and CV by SPIO-enhanced MRI were 10.3±3.7 and 0.19±0.08, respectively. For the non-LCG, mean values of SD and CV were 6.5±1.6 and 0.08±0.05, respectively. The mean APRI of the LCG and the non-LCG were 2.04±1.7 and 0.32±0.32, respectively. The RNHFI and APRI were significantly different between both groups (p<0.05). For the LCG, the bivariate correlation between SD and APRI revealed a statistically significant positive correlation (r=0.5, p<0.001). In both groups, there was no statistically significant correlation between CV and APRI.
Conclusion : A measurement of SD can be a simple and useful method for the
evaluation of hepatic fibrosis.
목차
등록된 정보가 없습니다.
참고문헌 (20)
참고문헌 신청
/ 2007 / Liver fibrosis: noninvasive assessment with MR elastography versus aspartate aminotransferase-to-platelet ratio index / Radiology 245 (2) : 458 ~ 466
Afdhal NH / 2004 / Evaluation of liver fibrosis: a concise review / Am J Gastroenterol 99 (6) : 1160 ~ 1174
Aguirre DA / 2006 / Liver fibrosis: noninvasive diagnosis with double contrast material-enhanced MR imaging / Radiology 239 (2) : 425 ~ 437
Aube C / 1999 / Ultrasonographic diagnosis of hepatic fibrosis or cirrhosis / J Hepatol 30 (3) : 472 ~ 478
Bedossa P / 1994 / Intraobserver and interobserver variations in liver biopsy interpretation in patients with chronic hepatitis C / Hepatology 20 (1 Pt 1) : 15 ~ 20
Afdhal NH / 2004 / Evaluation of liver fibrosis: a concise review / Am J Gastroenterol 99 (6) : 1160 ~ 1174
Aguirre DA / 2006 / Liver fibrosis: noninvasive diagnosis with double contrast material-enhanced MR imaging / Radiology 239 (2) : 425 ~ 437
Aube C / 1999 / Ultrasonographic diagnosis of hepatic fibrosis or cirrhosis / J Hepatol 30 (3) : 472 ~ 478
Bedossa P / 1994 / Intraobserver and interobserver variations in liver biopsy interpretation in patients with chronic hepatitis C / Hepatology 20 (1 Pt 1) : 15 ~ 20
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