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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2018.1
- 수록면
- 283 - 290 (8page)
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Background and Purpose The objective of this study was to determine the patterns of blood pressure (BP) changes during the head-up tilt (HUT) test, particularly in terms of its clinical significance for patients with orthostatic hypotension (OH). Methods OH was divided into four categories based on systolic BP changes occurring within the first 10 minutes of the HUT test: sustained orthostatic hypotension (SOH), progressive orthostatic hypotension (POH), orthostatic hypotension with partial recovery (OHPR), and transient orthostatic hypotension (TOH). Results In total, 151 patients were analyzed: 65 with SOH, 38 with POH, 21 with OHPR, and 27 with TOH. POH patients exhibited the greatest reduction in systolic BP after HUT and were also the most likely to develop symptoms requiring early termination of the HUT test (42.1%, p<0.001). Additionally, SOH patients exhibited smaller heart-rate variation with deep breathing values (p=0.003) and Valsalva ratios (p=0.022) compared to POH patients. The sweat volume was greatest in OHPR patients. Conclusions Clinical characteristics, including the findings of autonomic function tests, differed between the OH patient groups. This might reflect differences in the underlying pathophysiologic mechanisms. Determining the patterns of BP changes during the HUT test may facilitate the development of effective management strategies in patients with OH.
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참고문헌 (18)
참고문헌 신청
Phillip A. Low / 2015 / Orthostatic Hypotension: Mechanisms, Causes, Management / Journal of Clinical Neurology 11(3):220~226
Freeman R / 2011 / Consensus statement on the definition of orthostatic hypotension, neurally mediated syncope and the postural tachycardia syndrome / Clin Auton Res 21:69~72
Frith J / 2015 / Diagnosing orthostatic hypotension: a narrative review of the evidence / Br Med Bull 115:123~134
Low PA / 2008 / Management of neurogenic orthostatic hypotension: an update / Lancet Neurol 7:451~458
Metzler M / 2013 / Neurogenic orthostatic hypotension: pathophysiology, evaluation, and management / J Neurol 260:2212~2219
Freeman R / 2011 / Consensus statement on the definition of orthostatic hypotension, neurally mediated syncope and the postural tachycardia syndrome / Clin Auton Res 21:69~72
Frith J / 2015 / Diagnosing orthostatic hypotension: a narrative review of the evidence / Br Med Bull 115:123~134
Low PA / 2008 / Management of neurogenic orthostatic hypotension: an update / Lancet Neurol 7:451~458
Metzler M / 2013 / Neurogenic orthostatic hypotension: pathophysiology, evaluation, and management / J Neurol 260:2212~2219
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