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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2010.1
- 수록면
- 266 - 269 (4page)
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Cures for advanced hepatocellular carcinoma (HCC)with portal vein tumor thrombosis (PVTT) are rare and difficult. We report a case of pathologically confirmed complete remission of HCC induced by hepatic arterial infusion chemotherapy (HAIC). A 45-year-old male patient had a massive HCC in the right lobe of the liver and tumor thrombus in the right and main portal veins. He achieved a partial response after two cycles of HAIC with 5-fluorouracil (750 mg/m2) and cisplatin (25 mg/m2). After the completion of six cycles he received a curative partial hepatectomy, and histopathology revealed complete necrosis without any viable tumor cell. He was in good health at a 4-month follow-up. These results suggest that this regimen is a promising therapeutic modality for the treatment of advanced HCC with PVTT.
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참고문헌 (17)
참고문헌 신청
Aebersold DM / 2009 / Potential and future strategies for radiotherapy in hepatocellular carcinoma / Liver Int 29 : 145 ~ 146
Ando E / 2002 / Hepatic arterial infusion chemotherapy for advanced hepatocellular carcinoma with portal vein tumor thrombosis: analysis of 48 cases / Cancer 95 : 588 ~ 595
Cheng AL / 2009 / Efficacy and safety of sorafenib in patients in the Asia-Pacific region with advanced hepatocellular carcinoma: a phase III randomised, double-blind, placeb
Collins JM / 1984 / Pharmacologic rationale for regional drug delivery / J Clin Oncol 2 : 498 ~ 504
Eun JR / 2009 / Hepatic arterial infusion chemotherapy using high-dose 5-fluorouracil and cisplatin with or without interferon-a for the treatment of advanced hepatocellular
Ando E / 2002 / Hepatic arterial infusion chemotherapy for advanced hepatocellular carcinoma with portal vein tumor thrombosis: analysis of 48 cases / Cancer 95 : 588 ~ 595
Cheng AL / 2009 / Efficacy and safety of sorafenib in patients in the Asia-Pacific region with advanced hepatocellular carcinoma: a phase III randomised, double-blind, placeb
Collins JM / 1984 / Pharmacologic rationale for regional drug delivery / J Clin Oncol 2 : 498 ~ 504
Eun JR / 2009 / Hepatic arterial infusion chemotherapy using high-dose 5-fluorouracil and cisplatin with or without interferon-a for the treatment of advanced hepatocellular
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