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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 한국식품영양과학회 Preventive Nutrition and Food Science Preventive Nutrition and Food Science Vol.23 No.3
- 발행연도
- 2018.9
- 수록면
- 189 - 195 (7page)
- DOI
- 10.3746/pnf.2018.23.3.189
이용수
초록· 키워드
오류제보하기
The objective of this research was to determine the potential effects of Sargassum hystrix extracts (SHE) on the glucose levels, lipid profile, and pancreas of streptozotocin (STZ)-induced diabetic rats. SHE at 200, 300, and 400 mg/kg was administered orally to STZ-induced diabetic rats once daily for 15 days. Glucose levels, lipid profile, and weight of rats were measured in the normal state and on the 15th day. The histology of the pancreas was observed on the 15th day. The results showed that the preprandial and postprandial glucose levels in the group treated with SHE at 300 mg/kg were significantly reduced compared with those of the diabetes group. Additionally, the levels of triglycerides and cholesterol in the 300 mg/kg SHE group were significantly different from those in the diabetes group. However, the levels of high-density lipoprotein cholesterol and low-density lipoprotein cholesterol across the treatment groups did not have significant differences. Necrosis was found in all STZ-induced rats. SHE at a dose of 300 mg/kg had the best capability to lower the levels of preprandial and postprandial glucose and to prevent necrosis in diabetic rats.
목차
ABSTRACT
INTRODUCTION
MATERIALS AND METHODS
RESULTS AND DISCUSSION
REFERENCES
참고문헌 (30)
참고문헌 신청
[보고서] - WHO / 1999 / Definition, diagnosis and classification of diabetes mellitus and its complications: report of a WHO consultation. Part 1: diagnosis and classification of diabetes mellitus
[단행본] - IDF / 2015 / IDF diabetes atlas / International Diabetes Federation
[학술지(정기간행물)] - Tomkin GH / 2008 / Targets for intervention in dyslipidemia in diabetes / Diabetes Care 31 : S241 ~ S248
[학술지(정기간행물)] - Leiter LA / 2006 / Dyslipidemia in adults with diabetes / Can J Diabetes 30 : 230 ~ 240
[학술지(정기간행물)] - Moller DE / 2001 / New drug targets for type 2 diabetes and the metabolic syndrome / Nature 414 : 821 ~ 827
[단행본] - IDF / 2015 / IDF diabetes atlas / International Diabetes Federation
[학술지(정기간행물)] - Tomkin GH / 2008 / Targets for intervention in dyslipidemia in diabetes / Diabetes Care 31 : S241 ~ S248
[학술지(정기간행물)] - Leiter LA / 2006 / Dyslipidemia in adults with diabetes / Can J Diabetes 30 : 230 ~ 240
[학술지(정기간행물)] - Moller DE / 2001 / New drug targets for type 2 diabetes and the metabolic syndrome / Nature 414 : 821 ~ 827
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