메뉴 건너뛰기
.. 내서재 .. 알림
소속 기관/학교 인증
인증하면 논문, 학술자료 등을  무료로 열람할 수 있어요.
한국대학교, 누리자동차, 시립도서관 등 나의 기관을 확인해보세요
(국내 대학 90% 이상 구독 중)
로그인 회원가입 고객센터 ENG
주제분류

추천
검색
질문

논문 기본 정보

자료유형
학술저널
저자정보
저널정보
한국발육발달학회 한국발육발달학회지 한국발육발달학회지 제16권 제1호
발행연도
2008.3
수록면
27 - 33 (7page)

이용수

표지
📌
연구주제
📖
연구배경
🔬
연구방법
🏆
연구결과
AI에게 요청하기
추천
검색
질문

초록· 키워드

오류제보하기
Objective: To investigate whether beta-3 adrenergic receptor gene (ADRB3) polymorphism contributes the effects of treatment modality (mode) on weight loss induced changes in body composition and cardiovascular risk factors. Design: longitudinal, clinical intervention study of low-calorie diet (1000-1200 kcal/d) combined with exercise. Subjects: Ninety-five women with BMI 25 kg/m2 or more. All subjects were treated with low-calorie diet (Home Based-self Control Group) alone or combined with supervised exercise (In-Hospital Supervision Group). Measurements: The Trp64Arg polymorphism of the ADRB3gene was determined by PCR-RFLP. Body fatness and fat distribution parameters (Bioelectric impedance method, computed tomography scans), cardiorespiratory fitness (VO<sub>2max</sub>), and blood lipids at baseline and after 3months. Results: Both treatment modalities induced significant reductions in body weight and fatness. However, these changes were more pronounced in the in-hospital group. The in-hospital group also showed a greater increase in cardiorespiratory fitness whereas changes in other CVD risk factors did not differ between the treatment groups. The ADRB3 genotype was not associated with weight loss induced changes in body composition or CVD risk factors, except for DBP, which decreased more in the Trp homozygotes as compared to the Arg allele carriers (P<0.01). Conclusion: We conclude that the Trp64Arg allele of ADRB3 gene in Japanese middle-aged overweight and obese women is not significantly associated with a response to weight reduction. The effects of weight reduction may be affected intervention mode than genetic difference.

목차

등록된 정보가 없습니다.

참고문헌 (0)

참고문헌 신청

함께 읽어보면 좋을 논문

논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!

이 논문의 저자 정보

최근 본 자료

전체보기

댓글(0)

0

UCI(KEPA) : I410-ECN-0101-2017-692-001683173