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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2009.2
- 수록면
- 124 - 129 (6page)
이용수
초록· 키워드
오류제보하기
Antioxidant activities of the extract of red seaweed, Polysiphonia morrowii, were evaluated using several in vitro assay systems. Activity-guided fractionation revealed that the 90% MeOH fraction of the P. morrowii extract exhibited the highest antioxidant activity, and that this fraction had a high total phenolic content (135.7±5.0 ㎎ gallic acid/g extract). Therefore, the antioxidant activities of the 90% MeOH fraction against 2,2-diphenyl-1-picrylhydrazyl (DPPH), hydroxyl radical, reducing power, ferrous chelating, and hydrogen peroxide were investigated. The results revealed that the antioxidant activities of the 90% MeOH fraction were similar and/or superior to that of commercial antioxidants such as butylated hydroxyanisole (BHA) and butylated hydroxytoluene (BHT). In addition, the ability of the 90% MeOH fraction to inhibit oxidative damage to DNA was assessed by measuring the conversion of the supercoiled pBR322 plasmid DNA to the open circular form. The 90% MeOH fraction was found to significantly protect this hydroxyl radical-induced DNA damage in a dose-dependent manner. Taken together, these findings suggest that the 90% MeOH fraction of P. morrowii extract and/or its constituents has the potential for use as a new bioresource of antioxidants.
목차
Abstract
Introduction
Materials and Methods
Results and Discussion
Acknowledgments
References
참고문헌 (34)
참고문헌 신청
1. [학술지(정기간행물)] - Butterfield DA / 2002 / Nutritional approaches to combat oxidative stress in Alzheimer’s diseases / J. Nutr. Biochem. 13 : 444 ~ 461
2. [학술지(정기간행물)] - Debashis DD / 1997 / Hydroxyl radicals is the major causative factor in stress-induced gastric ulceration / Free Radical Bio. Med. 23 : 8 ~ 18
3. [학술지(정기간행물)] - Sussman MS / 1990 / Oxygen derived free radicals in reperfusion injury / Method Enzymol. 186 : 711 ~ 723
4. [학술지(정기간행물)] - Vajragupta O / 2000 / Comparative quantitative structure-activity study of radical scavengers / Bioorg. Med. Chem. 8 : 2617 ~ 2628
5. [학술지(정기간행물)] - Kumar KS / 2008 / Antioxidant potential of solvent extracts of Kappaphycus alvarezii (Doty) Doty-An edible seaweed / Food Chem. 107 : 289 ~ 295
2. [학술지(정기간행물)] - Debashis DD / 1997 / Hydroxyl radicals is the major causative factor in stress-induced gastric ulceration / Free Radical Bio. Med. 23 : 8 ~ 18
3. [학술지(정기간행물)] - Sussman MS / 1990 / Oxygen derived free radicals in reperfusion injury / Method Enzymol. 186 : 711 ~ 723
4. [학술지(정기간행물)] - Vajragupta O / 2000 / Comparative quantitative structure-activity study of radical scavengers / Bioorg. Med. Chem. 8 : 2617 ~ 2628
5. [학술지(정기간행물)] - Kumar KS / 2008 / Antioxidant potential of solvent extracts of Kappaphycus alvarezii (Doty) Doty-An edible seaweed / Food Chem. 107 : 289 ~ 295
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UCI(KEPA) : I410-ECN-0101-2013-573-000856530