지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 한국식품영양과학회 Journal of Food Science and Nutrition Journal of Food Science and Nutrition Vol.11 No.3
- 발행연도
- 2006.9
- 수록면
- 204 - 209 (6page)
이용수
초록· 키워드
오류제보하기
This study demonstrates that red yeast rice exhibits radical scavenging and antihypercholesterolemic activities in rats fed cholesterol. Sprague-Dawley male rats were divided to five dietary groups (normal, chol-control; and M-1, M-2 & M-3 administered 150, 300, and 500 ㎎/㎏ red yeast rice, respectively) and fed their respective diets for 4 weeks. No significant differences in food efficiency ratio (FER) were found among the five groups. The weight of perirenal fat pads decreased with increasing amounts of red yeast rice supplementation. There was a significant decrease in the levels of cholesterol in M-3 group fed red yeast rice with 500 ㎎/㎏ compared to those in the chol-control, M-1 and M-2 groups (p＜0.05). Among the rats fed the cholesterol-enriched diet, all groups fed red yeast rice showed higher concentration of the HDL cholesterol, but lower concentration of the LDL cholesterol than those of the chol-control group. The scavenging activity of the methanol extract from red yeast rice was increased with increasing amounts of the extract. The glutathione content in the normal group and in the M-3 group were higher than that in the other groups. The M-3 group showed similar hepatic glutathione contents to those of the normal group. These results suggest that red yeast rice may be safe and effective for lowering serum levels of total and LDL-cholesterol, ratio of non-HDL/HDL, and severity of experimental atherosclerosis.
목차
Abstract
INTRODUCTION
MATERIALS AND METHODS
RESULTS AND DISCUSSION
ACKNOWLEDGMENT
REFERENCES
참고문헌 (29)
참고문헌 신청
Stuart MD. 1979. Chinese Materia Medica-vegetable kingdom. Southern Material Center, Inc., Taipei, China.
Erdoğrul Ő, Azirak S. 2004. Review of the studies on the red yeast rice (Monascus purpureus). Turkish Electronic J Biotechnol 2: 37-49.
Ma J, Li Y, Ye Q, Li J, Hua Y, Ju D, Zhang D, Cooper R, Chang M. 2000. Constituents of red yeast rice, a traditional Chinese food and medicine. J Agric Food Chem 48: 5220-5225.
Nielson LB, Stender S, Kjeldsen K. 1993. Effect of lovastatin on cholesterol absorption in cholesterol-fed rabbits. Pharmacol Toxicol 72: 148-151.
Zhir BQ, Sievers RE, Sum YP, Isenberg WM, Parmley WW. 1992. Effect of lovastatin on suppression of atherosclerosis in lipid fed rabbits. J Cardiovasc Pharmacol 19: 246-255.
Erdoğrul Ő, Azirak S. 2004. Review of the studies on the red yeast rice (Monascus purpureus). Turkish Electronic J Biotechnol 2: 37-49.
Ma J, Li Y, Ye Q, Li J, Hua Y, Ju D, Zhang D, Cooper R, Chang M. 2000. Constituents of red yeast rice, a traditional Chinese food and medicine. J Agric Food Chem 48: 5220-5225.
Nielson LB, Stender S, Kjeldsen K. 1993. Effect of lovastatin on cholesterol absorption in cholesterol-fed rabbits. Pharmacol Toxicol 72: 148-151.
Zhir BQ, Sievers RE, Sum YP, Isenberg WM, Parmley WW. 1992. Effect of lovastatin on suppression of atherosclerosis in lipid fed rabbits. J Cardiovasc Pharmacol 19: 246-255.
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