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자료유형
학술저널
저자정보
저널정보
한국식품영양과학회 Journal of Food Science and Nutrition Journal of Food Science and Nutrition Vol.4 No.3
발행연도
1999.9
수록면
193 - 196 (4page)

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To investigate the effect of yam on the activity of benzo[a]pyrene hydroxylase (BPH), the key enzyme associated with polycyclic aromatic hydrocarbons (PAHs) metabolism, rats were fed a fiber free diet for 7 days, whereupon they were switched to experimental diets for another 7 days. Diets contained benzo[a]pyrene (BP, 400 ㎎/㎏ diet) and 25% or 50% yam powder (freeze dried and hot air dried). Diets containig pectin and cellulose were compared with diets containing yam. BPH activities were assessed in the liver, lung, kidney, stomach, small intestine and large intestine of rats. BP induced BPH activities in various tissues; 8 fold in liver, 28 in lung and stomach, and 32 in large intestine. The addition of yam significantly lowered BPH activity in liver, lung and stomach, and hot air dried yam was more effective than freeze dried yams. These data suggested that yam containing diet may influence carcinogen metabolism in liver and extrahepatic target tissues by altering activities of BPH and may reduce exposure of these tissues to dietary carcinogens.

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Abstract

INTRODUCTION

MATERIALS AND METHODS

RESULTS AND DISCUSSION

ACKNOWLEDGEMENTS

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