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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 환경독성보건학회 Environmental Analysis Health and Toxicology Environmental Analysis Health and Toxicology Vol.39 No.4
- 발행연도
- 2024.12
- 수록면
- 1 - 12 (12page)
이용수
초록· 키워드
오류제보하기
Boric acid (BA) is a weak acid and the simplest compound resulting from the dissolution of boron in water. There is great competition to determine whether boron is an essential or nonessential nutrient. Date molasses is a potent type of sweetener with valuable components, such as flavonoids and phenolics, and has significant health benefits. This study investigated the neuro-essentiality and neurotoxicity of boric acid boron in adult male albino rat cortex and cerebellum brain areas and the impact of date molasses treatment. Animals were grouped into the following groups: control, low and high boric acid doses, 10 and 500 mg/kg, respectively, with or without 250 mg/kg date molasses. The results revealed the ability of BAs to cross the blood–brain barrier and accumulate in the cerebellum and cortex, revealing the ability of date molasses to decrease BA accumulation at different time intervals. Additionally, the results varied between a nonsignificant increase or decrease in calcium ion content, monoamines (norepinephrine, dopamine, and serotonin), glucose, adenosine triphosphate, malondialdehyde and glutathione, depending on the BA dose. Moreover, date molasses mitigated any unwanted BA results. In conclusion, boric acid, which is within a permissible limit, could be essential and have a neuroprotective effect, whereas at a sublethal level, it could have a neurotoxic effect. Additionally, Date molasses can have neuroprotective effects and antagonize the neurotoxic effects of boric acid through its antioxidant and scavenging effects.
목차
Abstract
Introduction
Materials and Methods
Results
Discussion
References
참고문헌 (78)
참고문헌 신청
Majji M, Abzal SM, Jacob N, Maiti P, Choppella S, Ravva MK, et al. Efficient photocatalytic green hydrogen production using crystalline elemental Boron nanostructures under visible light. International Journal of Hydrogen Energy 2024;56:338-347. https://doi.org/10.1016/j.ijhydene.2023.12.113
Uzun S. Investigation of shielding properties of nuclear reactor control rod material boron carbide. Journal of Boron 2023;8(1):25-30. https://doi.org/10.30728/boron.1131336
Milewski J, Szczęśniak A, Szabłowski Ł, Martsinchyk A, Siekierski M, Dybinski O, et al. Molten borates fuel cells-Mathematical modeling and identification of performances. [cited Aug 16, 2024]. Available from: https://ssrn.com/abstract=4472245
Howe PD. A review of boron effects in the environment. Biol Trace Elem Res 1998;66(1-3):153-166. https://doi.org/10.1007/BF02783135
Białek M, Czauderna M, Krajewska KA, Przybylski W. Selected physiological effects of boron compounds for animals and humans. A review. Journal of Animal and Feed Sciences 2019;28:307–320. https://doi.org/10.22358/jafs/114546/2019
Uzun S. Investigation of shielding properties of nuclear reactor control rod material boron carbide. Journal of Boron 2023;8(1):25-30. https://doi.org/10.30728/boron.1131336
Milewski J, Szczęśniak A, Szabłowski Ł, Martsinchyk A, Siekierski M, Dybinski O, et al. Molten borates fuel cells-Mathematical modeling and identification of performances. [cited Aug 16, 2024]. Available from: https://ssrn.com/abstract=4472245
Howe PD. A review of boron effects in the environment. Biol Trace Elem Res 1998;66(1-3):153-166. https://doi.org/10.1007/BF02783135
Białek M, Czauderna M, Krajewska KA, Przybylski W. Selected physiological effects of boron compounds for animals and humans. A review. Journal of Animal and Feed Sciences 2019;28:307–320. https://doi.org/10.22358/jafs/114546/2019
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