지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한외과학회 Annals of Surgical Treatment and Research Annals of Surgical Treatment and Research Vol.107 No.4
- 발행연도
- 2024.10
- 수록면
- 187 - 194 (8page)
이용수
초록· 키워드
오류제보하기
Purpose: Adrenocortical carcinoma (ACC) is a rare primary carcinoma originating in the adrenal gland with a poor prognosis and a high recurrence rate. This study evaluated the risk factors associated with recurrence in patients with early stage ACC after curative surgical resection.
Methods: The present study retrospectively evaluated the risk factors for recurrence in 38 patients with stages 1 and 2 ACC who underwent curative resection between 1995 and 2020.
Results: Recurrence was observed in 21 patients (55.3%), with no significant difference between stages 1 and 2 ACC (P = 0.640). The overall recurrence rate was higher in patients who underwent minimally invasive surgery than open adrenalectomy (71.4% vs. 51.6%). Of the 33 patients with gross tumor margins negative for malignancy, 16 (48.5%) experienced tumor recurrence, and all 5 patients with positive and unknown gross resection margins had recurrence.
Recurrences were observed in 14 of the 30 patients (46.7%) negative for pathologic resection margins, 6 of the 7 patients (85.7%) with pathologically indeterminate margins, and 1 patient with pathologically positive margins.
Conclusion: The recurrence rates are high even in patients with early stage ACC, being higher in patients who undergo minimally invasive surgery than open adrenalectomy. Obtaining clear resection margins during surgery may reduce tumor recurrence; however, gross or pathologic margin safety was not a secure factor in preventing recurrence. None of the factors analyzed was a definitive predictor of poor prognosis
Methods: The present study retrospectively evaluated the risk factors for recurrence in 38 patients with stages 1 and 2 ACC who underwent curative resection between 1995 and 2020.
Results: Recurrence was observed in 21 patients (55.3%), with no significant difference between stages 1 and 2 ACC (P = 0.640). The overall recurrence rate was higher in patients who underwent minimally invasive surgery than open adrenalectomy (71.4% vs. 51.6%). Of the 33 patients with gross tumor margins negative for malignancy, 16 (48.5%) experienced tumor recurrence, and all 5 patients with positive and unknown gross resection margins had recurrence.
Recurrences were observed in 14 of the 30 patients (46.7%) negative for pathologic resection margins, 6 of the 7 patients (85.7%) with pathologically indeterminate margins, and 1 patient with pathologically positive margins.
Conclusion: The recurrence rates are high even in patients with early stage ACC, being higher in patients who undergo minimally invasive surgery than open adrenalectomy. Obtaining clear resection margins during surgery may reduce tumor recurrence; however, gross or pathologic margin safety was not a secure factor in preventing recurrence. None of the factors analyzed was a definitive predictor of poor prognosis
목차
INTRODUCTION
METHODS
RESULTS
DISCUSSION
REFERENCES
참고문헌 (0)
참고문헌 신청함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
A single center experience of adrenalectomy for adrenal tumors
KOREAN JOURNAL OF CLINICAL ONCOLOGY
2017 .12
-
Robotic Adrenalectomy: Why and When
대한외과학회 학술대회 초록집
2019 .10
-
Minimally Invasive Adrenal Surgery
Endocrinology and Metabolism
2020 .01
-
Predictors of Recurrence after Curative Resection in Patients with Early-Stage Non-Small Cell Lung Cancer
Tuberculosis and Respiratory Diseases
2015 .01
-
Estrogen-secreting adrenocortical carcinoma
Journal of Yeungnam Medical Science
2019 .01
-
Clinical Outcome after Adrenalectomy for Adrenal Metastasis: Laparoscopy versus Open Adrenalectomy
대한외과학회 학술대회 초록집
2022 .11
-
Estrogen-secreting adrenocortical carcinoma
영남의대학술지
2019 .01
-
Validation for models for tumor recurrence after liver transplantation in hepatectomy patients
Annals of Surgical Treatment and Research
2022 .03
-
Risk factors of recurrence in TNM stage I colorectal cancer
Annals of Surgical Treatment and Research
2023 .05
-
Which Patients Should We Follow up beyond 5 Years after Definitive Therapy for Localized Renal Cell Carcinoma?
Cancer Research and Treatment
2015 .01
-
Predictors of early recurrence following a curative resection in patients with a carcinoma of the ampulla of Vater
Annals of Surgical Treatment and Research
2020 .11
-
Clinical features of recurrence after hepatic resection for early-stage hepatocellular carcinoma and long-term survival outcomes of patients with recurrence: A multi-institutional analysis
Annals of Hepato-Biliary-Pancreatic Surgery
2022 .12
-
Prognosis of tongue squamous cell carcinoma associated with individual surgical margin and pathological features
대한구강악안면외과학회지
2022 .10
-
Differences in Prognostic Factors between Early and Late Recurrence Breast Cancers
Asian Pacific journal of cancer prevention : APJCP
2015 .01
-
Cribriform Pattern at the Surgical Margin is Highly Predictive of Biochemical Recurrence in Patients Undergoing Radical Prostatectomy
고신대학교 의과대학 학술지
2019 .01
-
Risk factors for poor survival after recurrence of hepatocellular carcinoma after liver transplantation
Annals of Surgical Treatment and Research
2021 .07
-
Substantial risk of recurrence even after 5 recurrence-free years in early-stage hepatocellular carcinoma patients
Clinical and Molecular Hepatology
2020 .01
-
Patterns of Locoregional Recurrence after Radical Cystectomy for Stage T3-4 Bladder Cancer: A Radiation Oncologist's Point of View
Yonsei Medical Journal
2021 .01
-
Prognosis after intrahepatic recurrence in the patients who underwent curative resection for hepatocellular carcinoma
Annals of Hepato-Biliary-Pancreatic Surgery
2020 .11
-
No Association of Positive Superficial and/or Deep Margins with Local Recurrence in Invasive Breast Cancer Treated with Breast-Conserving Surgery
Cancer Research and Treatment
2018 .01
최근 본 자료
댓글(0)
0
UCI(KEPA) : I410-151-25-02-091059530