지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2018.1
- 수록면
- 275 - 282 (8page)
이용수
초록· 키워드
오류제보하기
Purpose We evaluated the effect of positive superficial and/or deep margin status on local recurrence (LR) in invasive breast cancer treated with breast-conserving surgery (BCS) followed by radiotherapy. Materials and Methods In total, 3,403 stage 1 and 2 invasive breast cancer patients treated with BCS followed by radiotherapy from January 2000 to December 2008 were included in this study. These patients were divided into three groups according to margin status: clear resection margin status for all sections (group 1, n=3,195); positive margin status in superficial and/or deep sections (group 2, n=121); and positive peripheral parenchymal margin regardless of superficial and/or deep margin involvement (group 3, n=87). The LR-free survival between these three groups was compared and the prognostic role of margin status was analyzed. Results Across all groups, age, tumor size, nodal status, and human epidermal growth factor receptor 2 status did not significantly differ. High grade, positive extensive intraductal component, hormone receptor positivity, hormone therapy received, and chemotherapy not received were more prevalent in groups 2 and 3 than in group 1. Five-year LR rates in groups 1, 2, and 3 were 1.9%, 1.7%, and 7.7%, respectively. Multivariate analysis revealed that group 3 was a significant predictor for LR (hazard ratio [HR], 4.78; p < 0.001), but that positive superficial and/or deep margin was not (HR, 0.66; p=0.57). Conclusion Superficial and/or deep margin involvement following BCS is not an important predictor for LR.
목차
등록된 정보가 없습니다.
참고문헌 (28)
참고문헌 신청
Forrest AP / 1996 / Randomised controlled trial of conservation therapy for breast cancer: 6-year analysis of the Scottish trial. Scottish Cancer Trials Breast Group / Lancet 348:708~713
Malmstrom P / 2003 / Breast conservation surgery, with and without radiotherapy, in women with lymph node-negative breast cancer: a randomised clinical trial in a population with access to public mammography screening / Eur J Cancer 39:1690~1697
고범석 / 2012 / Changing Patterns in the Clinical Characteristics of Korean Breast Cancer from 1996-2010 Using an Online Nationwide Breast Cancer Database / Journal of Breast Cancer 15(4):393~400
Clarke M / 2005 / Effects of radiotherapy and of differences in the extent of surgery for early breast cancer on local recurrence and 15-year survival: an overview of the randomised trials / Lancet 366:2087~2106
Houssami N / 2010 / Meta-analysis of the impact of surgical margins on local recurrence in women with early-stage invasive breast cancer treated with breast-conserving therapy / Eur J Cancer 46:3219~3232
Malmstrom P / 2003 / Breast conservation surgery, with and without radiotherapy, in women with lymph node-negative breast cancer: a randomised clinical trial in a population with access to public mammography screening / Eur J Cancer 39:1690~1697
고범석 / 2012 / Changing Patterns in the Clinical Characteristics of Korean Breast Cancer from 1996-2010 Using an Online Nationwide Breast Cancer Database / Journal of Breast Cancer 15(4):393~400
Clarke M / 2005 / Effects of radiotherapy and of differences in the extent of surgery for early breast cancer on local recurrence and 15-year survival: an overview of the randomised trials / Lancet 366:2087~2106
Houssami N / 2010 / Meta-analysis of the impact of surgical margins on local recurrence in women with early-stage invasive breast cancer treated with breast-conserving therapy / Eur J Cancer 46:3219~3232
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
[Breast] Analysis of Recurrence Rate according to the Treatment Strategy in Positive or Close Margin after Breast-Conserving Surgery
대한외과학회 학술대회 초록집
2022 .11
-
Predictors of Positive or Close Surgical Margins in Breast-Conserving Surgery for Patients with Breast Cancer
Journal of Breast Disease
2018 .01
-
Hormonal Receptor Positivity and Clinical Multifocality Are Independent Predisposing Factors for Positive Margin Events in Breast-Conserving Surgery after Neoadjuvant Chemotherapy
Journal of Breast Disease
2015 .06
-
Impact of Resection Margin Distance on Survival of Pancreatic Cancer: A Systematic Review and Meta-Analysis
Cancer Research and Treatment
2017 .07
-
Intraoperative Specimen Mammography for Margin Assessment in Breast-Conserving Surgery
Journal of Breast Cancer
2019 .01
-
The Clinical Correlation between Margin Status and Local Recurrence in Unfavorable Breast Cancer Subtype
대한외과학회 학술대회 초록집
2020 .11
-
Oncologic outcomes according to the location and status of resection margin in pancreas head cancer: role of radiation therapy in R1 resection
Annals of Surgical Treatment and Research
2022 .01
-
Impact of Using Intra-Operative Ultrasound Guided Breast-Conserving Surgery on Positive Margin and Re-Excision Rates in Breast Cancer Cases with Current SSO/ASTRO Guidelines
Asian Pacific journal of cancer prevention : APJCP
2016 .01
-
Nomogram for Predicting Positive Resection Margin after Breast-Conserving Surgery Following Neoadjuvant Chemotherapy
대한외과학회 학술대회 초록집
2022 .05
-
What Is Optimal Surgical Width and Margin for Breast Conserving Surgery after Neoadjuvant Chemotherapy?
대한외과학회 학술대회 초록집
2021 .11
-
Prognosis of tongue squamous cell carcinoma associated with individual surgical margin and pathological features
대한구강악안면외과학회지
2022 .10
-
Comparison of Re-excision Rate in Breast Conserving Surgery with or without Intraoperative Frozen Section for Margin Assessment
대한외과학회 학술대회 초록집
2020 .11
-
Incidence and Predictors of Recurrence among Breast Cancer Patients in Black Lion Specialized Hospital Adult Oncology Unit, Addis Ababa, Ethiopia: Retrospective Follow-up Study with Survival Analysis
대한암예방학회지
2020 .01
-
Comparison of Ipsilateral Breast Tumor Recurrence Rate between Re-Excision and Radiotherapy Only Group When Surgical Margin Involvement of DCIS after Breast-Conserving Surgery
대한외과학회 학술대회 초록집
2021 .05
-
호르몬 수용체 약양성 유방암과 삼중음성 유방암의 치료 예후
Journal of Breast Disease
2019 .01
-
Interpretation of Pathologic Margin after Endoscopic Resection of Gastrointestinal Stromal Tumor
Clinical Endoscopy
2016 .01
-
Early stage adrenocortical carcinoma—what contributes to poor prognosis after adrenalectomy? A retrospective cohort study
Annals of Surgical Treatment and Research
2024 .10
-
Oncologic safety of breast-conserving surgery in breast cancer patients under the age of 35
KOREAN JOURNAL OF CLINICAL ONCOLOGY
2017 .06
-
Cribriform Pattern at the Surgical Margin is Highly Predictive of Biochemical Recurrence in Patients Undergoing Radical Prostatectomy
고신대학교 의과대학 학술지
2019 .01
-
3부위 최적맥파의 주파(h1) 비율 분석을 통한 전체 체순환 평가방법
Korean Journal of Acupuncture
2016 .01
이 논문의 저자 정보
최근 본 자료
댓글(0)
0